Tag: lipid nanoparticles

A review in Discover Oncology examines how engineered materials can address manufacturing, delivery, and safety bottlenecks across cellular immunotherapy.

Researchers designed three lipid nanoparticle mRNA vaccines targeting swine influenza hemagglutinin, finding that a swine-to-human antigen induced the broadest cross-reactive ...

A scientific review assesses how nanotechnology-enabled drug delivery systems enhance pharmacokinetics and lung targeting for COVID-19 therapeutics while confronting substantial ...

A scientific review in Discover Biotechnology evaluates next-generation gene-editing, RNA-based, and engineered immune-cell platforms for cancer treatment and immune modulation.

A scientific review in Discover Nano highlights the therapeutic progress and ongoing translational hurdles facing lipid nanoparticle-mediated mRNA delivery systems ...

Researchers and trainees at an international symposium presented emerging RNA mechanisms spanning transcription dynamics, structural regulation, and targeted therapeutic delivery.

Nagoya University researchers have developed a non-destructive single-vesicle analysis technique that reads internal microRNAs and surface proteins to pinpoint the ...

A systematic review indicates that while engineered exosomes offer unique biological delivery advantages for cancer therapy, their clinical translation remains ...

A 2025 review in Discover Pharmaceutical Sciences details the analytical techniques used to characterize lipid-based nanotherapeutics, covering physicochemical, chemical, and ...

A comprehensive review details how microneedle patches integrate solid-state stabilization, skin-targeted delivery, programmable booster dosing, and on-patient optical documentation into ...

The study, published in Cellular & Molecular Biology Letters, introduces a lipid nanoparticle system loaded with ferrostatin-1 and functionalized with ...

A comprehensive review details technological breakthroughs in epigenome editing platforms and highlights emerging in vivo strategies for disease modeling and ...

Researchers designed hybrid nanoparticles combining reprogrammed macrophage nanovesicles and lipid carriers to direct therapeutic siRNA into damaged cardiac tissue while ...

In rodent models and patient-derived ascites samples, lipid nanoparticles degraded TREM2 and reprogrammed tumour-associated macrophages into chimeric antigen receptor cells ...

A new review proposes matching lipid nanoparticle designs to specific Alzheimer's disease pathways, from neuronal BACE1 siRNA delivery to microglia-targeted ...

Researchers engineered lipid nanoparticles around the antihistamine hydroxyzine, achieving brain delivery of mRNA, CRISPR components and a radioprotective interleukin in ...

A new review examines how cationic lipid-based nanoparticles carry RNA, proteins and peptides into cancer cells, and why clinical translation ...

A new review outlines how lipid-based nanomedicines could deliver pathway-specific siRNA to treat hepatocellular carcinoma, highlighting delivery design, preclinical candidates ...

A new review argues that engineered nanomaterials interact with biology through a shared set of interfacial processes that determine their ...

A new review argues that CRISPR antivirals, especially RNA-targeting Cas13 systems, can suppress respiratory viruses in preclinical models, with lung ...