Tag: lipid nanoparticles

MIT chemical engineers have built an automated, self-correcting platform that rapidly produces lipid nanoparticles of precisely controlled sizes and shapes, ...

A new critical review argues that artificial intelligence has accelerated epitope prediction for multi-epitope vaccines, but chemical developability, nanocarrier formulation ...

Researchers converted Duchenne patient stem-cell teratomas into humanized models in which both gene-corrected cell transplants and lipid nanoparticle base editing ...

New EG95-based mRNA-lipid nanoparticle vaccines induced stronger and longer-lasting immunity against cystic echinococcosis than conventional subunit vaccines in mice and ...

New research shows that synthetic lipid nanoparticles trigger irregular calcium signals in cells partly through the pain-sensing ion channel TRPA1, ...

A new review synthesizes preclinical and clinical evidence showing that lipid nanoparticle biodistribution, mRNA persistence, and protein expression are distinct ...

The Journal of Pharmaceutical Investigation has announced a January 2027 special issue, with submissions due June 30, 2026, dedicated to ...

A new review details how chimeric antigen receptor-engineered macrophages are overcoming the barriers that stalled CAR-T therapy in solid tumors, ...

A new review details how the matrix protein SPP1 orchestrates immunosuppression across the tumor microenvironment and outlines emerging strategies to ...

Scientists have shown that tuning the internal nanoscale curvature of lipid nanoparticles can dramatically enhance the antibiotic daptomycin's ability to ...

A new study in Genome Medicine reveals that lactate produced by inflamed gut cells fuels an ACSS2-driven histone lactylation feedback ...

Researchers have engineered a custom ionizable lipid nanoparticle that delivers CAR-encoding mRNA into human T cells with over 90 percent ...

A HER2-targeted mRNA lipid nanoparticle vaccine combined with fractionated radiotherapy suppressed tumor growth and reprogrammed the immune microenvironment in a ...

Researchers at the University of Catania have built a modular computational framework that ranks RNA-lipid nanoparticle formulations for safety and ...

A new review in Materials Today Bio proposes a bottleneck-first framework for evaluating antigen delivery platforms in therapeutic cancer vaccines, ...

In a groundbreaking leap forward for HIV treatment strategies, a team of researchers has unveiled a highly efficient method for ...

Chemists succeed in artificially manufacturing important building blocks for mRNA vaccines Chemists at Otto von Guericke University Magdeburg have, in ...