Tag: gene expression

Propolis and dexpanthenol were associated with distinct, gene-specific changes in inflammatory, gasdermin, and heat-shock mRNA expression in the brains of ...

Researchers identified 22 cell-type-specific genetic associations linking immune cell gene expression to epigenetic aging clocks through Mendelian randomization and colocalization ...

An exploratory multi-dataset transcriptomic analysis identified host autophagy-related gene signatures in tuberculosis-diabetes comorbidity, finding that the observed transcriptional alterations are ...

Researchers used mass spectrometry-based proteomics to identify 5,282 proteins across in vitro overexpression and knockdown models of CALHM6.

A systematic review of 28 RNA sequencing studies shows biological pathway convergence in diabetic kidney disease despite substantial methodological heterogeneity.

Deficiency in the conserved vertebrate master male-sex-determining gene dmrt1 leads to extensive alterations in DNA methylation in the brain and ...

A randomized trial found that daily supplementation with a curcumin and pomegranate polyphenol blend modulated immune pathway gene expression in ...

A two-gene transcriptomic signature combining JAK1 and GATA3 reproducibly distinguished sepsis from controls across independent cohorts while tracking shifts from ...

Separately built female and male genetic scores based on depression-related brain gene expression show sex-specific links to brain structure and ...

Comparative analysis of gene expression in embryonic legs and larval wings of the butterfly Bicyclus anynana reveals evidence of a ...

A cross-site multiomic analysis of 194 patients has uncovered three distinct molecular subtypes of neuroendocrine tumors that provide prognostic value ...

A study of 932 breast cancer patients finds that DCE-MRI radiomic subgroups and vascular gene-expression subgroups capture complementary, non-overlapping dimensions ...

A study of meningioma tumor samples and cell lines links NF2 alterations with upregulated EZH2 and E2F1 pathways to aggressive ...

A study of 72 Acinetobacter baumannii clinical isolates from an Egyptian hospital found that 86 percent formed biofilms, resistance to ...

Researchers used low-frequency sound waves to assemble human mesenchymal stromal cell spheroids into stable rings within fibrin hydrogels and showed ...

Whole-blood transcriptomics in a randomized phase 2 trial sub-study found distinct early gene expression changes with linezolid-containing tuberculosis regimens and ...

An injectable hydrogel carrying lab-grown cartilage microtissues preserved disc height and shifted anabolic and catabolic gene expression toward regeneration in ...

In a 50-day rat experiment, oral turmeric extract rich in curcumin reduced hydrogen peroxide-induced liver enzyme elevations, histological damage, and ...

Scientists built an inducible human cell line that overproduces TDP-43, triggering toxicity, mislocalization, and gene expression changes that overlap with ...

Whole-genome sequencing of 1,043 French Polynesian participants reveals hundreds of variants absent from global reference datasets that shape metabolites, gene ...