Tag: gene expression

Researchers introduced SWIMR, a statistical framework that integrates multiple single-cell RNA sequencing references to improve cell-type deconvolution accuracy in spatial ...

A two-cohort human transcriptomic study demonstrates that elevated MDK expression and suppressed fatty-acid beta-oxidation form a reciprocal transcriptional signature in ...

Researchers developed a two-colour autoluminescent reporter system that separates plant gene expression signals from metabolic noise without requiring external substrate.

A study published in Frontiers in Cell and Developmental Biology identifies CD36, SESN3, and HMOX1 as key oxidative stress-associated biomarkers ...

A machine learning and bioinformatics study identified six potential hub genes linking the organophosphate flame retardant TDCPP to endometrial cancer ...

A genome-wide survey of maize identified 36 SPL transcription factor genes whose expression shifts under salinity and temperature stress.

Researchers identified nine Caspase9 polymorphisms in Qianhua Mutton Merino rams and linked the g.129 C > T locus significantly to ...

A multi-omics Mendelian randomization analysis identified 13 candidate mitochondrial-related genes linked to congenital heart disease susceptibility, with POLG and EARS2 ...

Researchers identified divergent physiological and transcriptomic mechanisms underlying chilling tolerance in zoysiagrass cultivars and demonstrated that exogenous chitosan can protect ...

A laboratory study found that raising the temperature from 18 °C to 22 °C shifted gene expression in Pseudomonas aeruginosa ...

Serial subculture of Candida auris under microaerobic conditions persistently enhanced adhesion, reduced antifungal susceptibility, and attenuated virulence in Galleria mellonella.

A multi-cohort retrospective investigation and laboratory analysis revealed that downregulation of the lipid metabolism gene AGPAT4 in thyroid cancer distinguishes ...

Researchers applied integrative network analysis to over 1,400 bulk RNA sequencing samples to predict cell type-enriched transcriptomes across four human ...

A computational workflow named CELLIA pairs statistical differential expression metrics with curated marker databases to improve the accuracy and consistency ...

An integrative bioinformatics study with experimental validation identifies PRICKLE1 as a potential hub gene and biomarker in keloids.

Researchers have developed SAIGE-QTL, an efficient Poisson mixed-model framework that directly analyzes single-cell read counts to substantially expand expression quantitative ...

Researchers analyzed age-dependent fruit quality changes and coordinated branch molecular mechanisms across four-, five-, and six-year-old sea buckthorn trees.

Researchers evaluated Polygonatum cyrtonema samples across five geographical origins to identify key antioxidant polyphenols and their biosynthetic genes.

A multi-omics study using East Asian-specific models has prioritized novel susceptibility genes and epigenetic markers linked to lung cancer risk.

Computational single-cell transcriptomics and in vitro validation reveal eleven distinct bone marrow immune states and complex CD274 communication networks in ...