Tag: ferroptosis

A new review proposes an 'acute storm versus chronic siege' framework distinguishing how acute and chronic liver disease injure the ...

A new open-access review in Cell Biology and Toxicology examines how ferroptosis, an iron-dependent form of cell death, may contribute ...

A new mouse study reports that the adipokine asprosin promotes obesity by inducing ferroptosis in brown adipocytes through inhibition of ...

A dissolving microneedle patch carrying an oxygen-vacancy-rich Fe3O4@SnO2 nanozyme and gallic acid suppressed 4T1 tumors in mice by 88.4 percent ...

A study in Clinical and Experimental Medicine reports that TRIM11 protects microglia from oxidative stress and ferroptosis during cerebral ischemia ...

A small prospective study in Iraq found that ferroptosis-related and inflammatory blood markers in pulmonary tuberculosis patients shifted toward control ...

A new review maps how biomaterials can exploit cholesterol metabolism in cancer while warning that most mechanistic claims remain unproven.

A copper-based RNAi nanocomplex that silences Cpt1a achieved 73.87 percent tumor growth inhibition and near-complete suppression of lung metastasis in ...

RNA modification networks and metabolic reprogramming establish reciprocal circuits that drive hepatocellular carcinoma progression and therapeutic resistance.

A new review argues mitochondria act as mechanometabolic conductors of cancer metastasis while warning that shared peroxisomal machinery complicates drug ...

A critical review finds that Salvia miltiorrhiza compounds can protect hepatocytes and suppress fibrogenic stellate cells, but no single intervention ...

A new perspective proposes that G6PD deficiency acts as a metabolic redox checkpoint in red blood cells, shifting them from ...

A new review in Medical Oncology details how the mitochondrial transporter SLC25A39 links glutathione import, iron-sulfur cluster assembly and tumor ...

A review of preclinical evidence finds that lipid-storage, fatty-acid oxidation, phospholipid and antioxidant programs can influence multiple processes linked to ...

Researchers built macrophage membrane-coated nanoparticles that co-deliver celastrol and ADAM17-silencing siRNA to injured heart tissue, easing doxorubicin-induced cardiomyopathy in mice.

A Nature Neuroscience study in mouse and cell models reports that losing the Parkinson's risk protein NgBR in microglia triggers ...

A new review maps how the self-activating enzyme ASRGL1 shows pro-tumor activity in liver, cervical and prostate cancers while behaving ...

A review of 86 cellular, animal and clinical studies reports multiple antitumor mechanisms for ginsenosides in liver-cancer models, while noting ...

A HEK293-cell study found that VPS13A knockdown increased oxidant-associated lipid peroxidation and was accompanied by iron-linked endolysosomal and mitochondrial changes.

A focused preclinical review finds that natural products can suppress NRF2-linked antioxidant defenses in hepatocellular carcinoma while protecting non-malignant liver ...