Tag: ferroptosis

New research reveals that the Staphylococcus aureus virulence factor Sph disrupts mitochondrial cristae through Mic60, releasing mtDNA that activates the ...

A new single-cell and animal study links SLC7A11-high astrocyte states to antioxidant failure and synaptic remodeling in multiple sclerosis, pointing ...

New research shows that synthetic ligands for the orphan nuclear receptors NR4A1 and NR4A2 induce iron-dependent cell death in colon ...

A new review in Medical Oncology argues that simultaneously inducing the iron-driven cell death ferroptosis and the copper-driven cuproptosis, tuned ...

A new review maps how the mycotoxin deoxynivalenol hijacks ribosomal and cellular signaling networks to drive intestinal, immune, neurological and ...

A gut microbiota-derived antioxidant metabolite, 2,8-dihydroxyquinoline, reverses oligoasthenozoospermia in mice by binding the kinase MAPK14 and blocking ferroptotic death of ...

A single-cell atlas of 554 human cataract capsules reveals that nerve-like fibers invade the aging lens through an NRG1-ERBB3 signaling ...

A new review in the Journal of Translational Medicine argues that mitochondria-associated endoplasmic reticulum membranes integrate lipid metabolism and ferroptosis ...

A new review in Medical Oncology maps how the tumor microenvironment can either amplify or suppress ferroptosis, the iron-dependent cell ...

A new iScience review argues that ferroptosis, an iron-driven form of cell death, links tumor and immune signals to muscle ...

A new study in Genome Medicine reveals that lactate produced by inflamed gut cells fuels an ACSS2-driven histone lactylation feedback ...

A new review proposes that the ratio of monounsaturated to polyunsaturated membrane phospholipids acts as a tunable rheostat controlling ferroptosis ...

A new Nature Cancer study reveals that the kinase GSK3β in colorectal tumor cells drives fumarate accumulation that epigenetically reprograms ...

New research reveals that the RNA splicing factor LUC7L2 drives ferroptotic kidney damage from cisplatin by corrupting the splicing of ...

Researchers found that DNA methylation patterns in the STEAP3 iron-processing gene, measured in cerebrospinal fluid after a brain aneurysm rupture, ...

A new review in the Journal of Translational Medicine maps how NCOA4-mediated ferritinophagy controls iron release and ferroptosis, cataloguing small-molecule ...

In a groundbreaking study poised to redefine therapeutic approaches in oncology, researchers have illuminated the intricate relationship between iron homeostasis ...

In an intriguing exploration of the intersection between reproductive health and metabolic disorders, a recent study has shed light on ...

In a groundbreaking study that promises to reshape our understanding of neurodegenerative and metabolic disorders, researchers have identified a novel ...

A groundbreaking study has emerged from the frontiers of cell biology, shedding unprecedented light on the molecular mechanisms that govern ...