Tag: Drug delivery

A mouse study found that directly reducing lung cancer cells’ dependence on phospholipase D1 significantly slowed tumor growth, but clinical ...

A preclinical study found that fucoidan-coated zein nanoparticles increased psoralen uptake in 4T1 breast-cancer cells, prolonged tumor-associated retention in mice, ...

A laboratory cell study found that doxorubicin-loaded, silica-coated iron oxide nanoparticles produced lower viability in HL60 leukaemia cells than free ...

Researchers engineered methylselenol donors that release their payload under ultraviolet light or activation by the tumor-associated enzyme hNQO1, with cell-based ...

A study of 306 microfluidic liposome formulations found that gradient boosting predicted polydispersity better than one prior benchmark and identified ...

A new review finds that exosome and small extracellular vesicle therapies improve the diabetic wound environment, but direct evidence that ...

A new cross-platform review of eighteen FDA-approved RNA therapeutics finds that adverse effects depend more on delivery chemistry and administration ...

A new review in Advanced Composites and Hybrid Materials explains why polymeric micelle drug carriers remain fragile in the bloodstream ...

Researchers developed ebastine-loaded Solusome nanovesicle oral lyophilisates that disintegrate in seconds and raised the drug's oral bioavailability 3.21-fold in rats.

A new review in Genes & Diseases outlines how co-targeting EGFR alongside other tumor-driving molecules, delivered via nanocarriers, could enable ...

A new thermoresponsive gel containing levofloxacin-loaded nanoparticles and hyaluronic acid significantly accelerates the healing of infected diabetic ulcers in animal ...

Psoriasis is one of dermatology's most stubborn targets, and the reason lies in the skin itself. In patients with the ...

Chemotherapy saves lives, but it can also leave chaos in its wake. One of the most widely used anticancer drugs, ...

Researchers preconditioned mesenchymal stem cells with the bacterial peptide plantaricin, producing smaller, protein-rich microvesicles that selectively triggered apoptosis in colon ...

A new review in Pharmacia charts how magnetic nanoparticles, metal-organic frameworks, and ROS-responsive carriers are transforming targeted cancer therapy and ...

A new review argues that the bottleneck for RNAi therapies in Alzheimer's, Parkinson's and Huntington's disease is not gene silencing ...

A comprehensive review in Discover Chemistry evaluates advanced formulation strategies, from solid dispersions and novel salt forms to polymeric micelles ...

A new review argues that plant-derived extracellular vesicles can both deliver and amplify the anticancer power of plant natural products, ...

Infant neuroblastoma is one of the most clinically paradoxical cancers in medicine. Diagnosed during the first year of life, it ...

Researchers developed a near-infrared-responsive microneedle patch that delivers cryptochlorogenic acid via ZIF-8 nanoparticles to inhibit MMP3, MMP9 and MMP13 and ...