Microbes Emerge as Sustainable Biofactories for Silver and Gold Nanoparticles in Biomedicine
A new mini review summarizes how bacteria, fungi, and algae sustainably produce silver and gold nanoparticles with potential antimicrobial, anticancer, ...
Tag: Drug delivery
Antibody Targeting of Olfactory Epithelium Boosts Nose-to-Brain Drug Delivery in Mice
In mice, an antibody targeting CADM1 in the olfactory epithelium delivered significantly higher brain levels of the drug MMAE than ...
Phosphorylcholine Copolymers Reviewed From Synthesis to Drug Delivery
A new review synthesizes how phosphorylcholine-containing block and random copolymers are made, characterized, and applied in drug delivery and antifouling ...
Gallium-68 PET tracking reveals where nanoerythrosomes travel in rats
A new study shows gallium-68-labeled nanoerythrosomes can be tracked by PET in rats, with significantly higher uptake in the liver, ...
Iron-Engineered Nanoplatform Delivers DMDD and Targets Immune Checkpoints in Breast Cancer Model
An iron-engineered mesoporous organosilica nanoplatform improved delivery of the natural compound DMDD and inhibited breast tumor growth in preclinical models ...
Magnetic nanoparticles steer doxorubicin toward triple-negative breast tumors
Hyaluronic acid-decorated, iron oxide-loaded PLGA nanoparticles guided by a pulsed electromagnetic field increased tumor accumulation of doxorubicin roughly 1.5-fold in ...
Artificial synapses that release neurotransmitters aim to go beyond electrical stimulation
A new perspective argues that artificial synapses delivering neurotransmitters could overcome the limits of drugs and electrical stimulation, though surgical ...
Ionic liquids offer greener route to collagen extraction and advanced materials
A new review finds ionic liquids can extract collagen from skins and tanned leather more efficiently and sustainably than conventional ...
Chemical antibodies show promise against viruses and neglected tropical diseases
A new review evaluates how short synthetic nucleic acid molecules called aptamers could improve diagnosis and treatment of viral and ...
Ultrasound-Boosted Implant Aims to Push Drugs Deeper Into the Brain
MIT researchers have built an implantable device that pairs a 24-transducer ultrasound array with a drug-delivery cannula to spread therapeutic ...
Laser-carved microvalves turn brain catheters into one-way streets against backflow
Researchers at Shanghai Jiao Tong University and Beijing Institute of Technology have used femtosecond laser writing to carve passive Tesla ...
Scientists Build a Cephalosporin Triggered Prodrug That Delivers an Antibiotic Nucleoside in Resistant Bacteria
Researchers have synthesized cephalosporin-based pronucleotides of AZT that are cleaved by bacterial β-lactamases, achieving a first modest proof of concept ...
Fungal extracellular vesicles emerge as immune messengers and possible drug carriers
A new review synthesizes how vesicles released by pathogenic fungi carry molecular cargo that shapes host immunity, drives biofilm drug ...
Plant Compounds Meet Smart Hydrogels as AI and 3D Printing Reshape Chronic Wound Care
A new review maps how phytochemical-loaded hydrogel systems, enhanced by artificial intelligence and 3D printing, are being engineered to overcome ...
Smart Hydrogel Delivers CRISPR Gene Editing to Treat Degenerating Spinal Discs in Rats
A pH- and ROS-responsive hydrogel carrying CRISPR-Cas9 silenced the TRPV4 calcium channel in rat discs, restoring autophagic flux and slowing ...
Cartilage-binding coacervate lubricant eases osteoarthritis in animal models
A biomimetic coacervate that binds cartilage, lubricates joints and delivers anti-inflammatory drugs and stem cells reduced cartilage degradation in rat ...
Smart Hydrogel Turns Wound Chemistry Into Healing Nitric Oxide
A ROS-responsive GelMA hydrogel loaded with L-arginine releases nitric oxide on demand in inflamed wounds, achieving 93.7% closure in rats ...
Same Drug, Different Cells: Why mTOR Inhibition in Plaques Defies Simple Rules
A new review argues that mTOR's effects in atherosclerotic plaques depend on cell state, plaque niche, signalling complex and drug ...
Aptamers Emerge as Programmable Building Blocks for Precision Cancer Immunotherapy
A new review maps how engineered DNA and RNA aptamers could enable targeted delivery and tumor microenvironment remodeling in precision ...
Magnetic Gut Robot Delays Biologic Release
Researchers developed a biodegradable magnetic robot that uses microneedles to deliver biologics to the intestine with delayed onset and sustained ...
