Tag: Cellular Senescence

Researchers found that ethanol extracts and flavone glycosides from Dicliptera chinensis reduced cellular senescence markers in neuroblastoma cells and improved ...

Researchers developed SenescenceBioKG, a knowledge graph extracting biomaterial design and regeneration patterns across 283 full-text studies, highlighting responsive mechanisms alongside ...

Researchers have discovered that vanadyl sulfate acts as a selective senolytic agent by disrupting vulnerable protein-folding machinery in senescent cells, ...

Researchers discovered that genetic deletion of the phosphatase MKP-2 reduces cellular senescence, remodels adipose lipid composition, and extends median lifespan ...

A comprehensive review outlines how aging and tumor signaling remodel circulating platelets into hyperreactive, immunosuppressive cellular fragments that drive thromboinflammation ...

A prospective study of older elective cardiac surgery patients reveals that preoperative levels of cellular senescence proteins IGFBP-1 and IGFBP-4 ...

Researchers have identified claudin-1 as a cell-specific marker that distinguishes stress-induced premature senescence from replicative senescence in human vascular smooth ...

Researchers report that restoring the chemical tag lysine crotonylation through sodium crotonate rejuvenates aging adipose-derived stem cells and improves their ...

An ethanolic extract of Tinospora cordifolia attenuated D-galactose-induced aging in mice by restoring oxidative, inflammatory, and pro-longevity biomarkers in liver ...

A new review argues that senescent cells and their inflammatory secretions may sustain chronic skin inflammation, with the strongest evidence ...

A new review maps the biomarkers, transcriptomic signatures and methodological pitfalls involved in reliably identifying senescent vascular smooth muscle cells ...

Higher dietary intake of the green tea compound EGCG was associated with slower biological aging and lower mortality in a ...

A new mini-review proposes that durable senescence-like states in dorsal root ganglion sensory neurons may help explain why pain persists ...

A new mouse study shows the approved cystic fibrosis drug ivacaftor reduced pulmonary fibrosis by suppressing senescence in alveolar type ...

A new study in Cell Death Discovery shows that the PRMT6–SIRT5–HADHA pathway protects bone-forming osteoblasts from R-loop-induced DNA damage during ...

Researchers found that elevated prostaglandin E2 triggers early macrophage senescence that spreads to uterine fibroblasts through IL-1beta signaling, driving fibrosis ...

A new review in Cell Regeneration explains why transient senescent cells support muscle repair while persistent senescence in aged or ...

A new review describes how aberrant DNA methylation and premature senescence of fat cell precursors drive adipose tissue dysfunction in ...

A 450-nanometer blue laser combined with the photosensitizer sinoporphyrin sodium suppressed lung cancer cells and xenograft tumors by triggering ROS-dependent ...

A new review argues that mushrooms and the antioxidant L-ergothioneine show anti-aging effects in laboratory models, while human evidence remains ...