Tag: cancer stem cells

A comprehensive mechanistic review evaluates how chromatin regulation, RNA modifications, and noncoding RNA networks govern cancer stem cell plasticity and ...

Single-cell transcriptomic profiling of lung adenocarcinoma tissues reveals how undifferentiated cancer stem cell subpopulations expand in late-stage tumors and harbor ...

Researchers have proposed a self-reinforcing RUNX2 and TGF-beta feedback loop as a working hypothesis to explain chemoresistance in triple-negative breast ...

Researchers found that sodium-calcium exchanger NCX1 regulates directional migration and VE-cadherin-positive vasculogenic mimicry in mesenchymal glioblastoma stem cell models.

Study identifies that MARK2 promotes stem cell characteristics and drug resistance in hepatocellular carcinoma through Wnt and PI3K/AKT signaling.

A review highlights how the orphan nuclear receptor ESRRB regulates stem cell pluripotency and exhibits context-dependent tumor-promoting or tumor-suppressing roles ...

A scientific review evaluates evidence on how cytomegalovirus may influence cancer stem cells and therapy resistance while noting that tumor ...

A new study in Cellular Oncology identifies GTSE1 as a key driver of esophageal squamous cell carcinoma stemness through the ...

A review in Discover Oncology details how Notch signaling pathways drive cancer drug resistance through mechanisms involving apoptosis, DNA repair, ...

A study in the Journal of Translational Medicine reveals that Realgar eliminates triple-negative breast cancer stem cells by degrading the ...

Targeting casein kinase II alongside MEK signaling suppresses tumor growth and depletes cancer stem cells in metastatic colorectal cancer organoids.

A new review maps how artificial intelligence could overcome resistance and safety barriers in cancer stem cell-targeted cellular immunotherapy, while ...

A new review in Cell Division details how colorectal cancer cells form their own blood-supply channels through vasculogenic mimicry, a ...

A new review examines how plant-derived compounds such as polyphenols, flavonoids, alkaloids and isothiocyanates may target the breast cancer stem ...

A new review proposes that mature tumor cells can dedifferentiate into cancer stem cells, acting as a non-genetic engine of ...

Adapting to serine and glycine scarcity rewires mitochondrial metabolism in pancreatic cancer cells and increases their cancer stem cell frequency, ...

A new open-access review maps how stem cell-derived extracellular vesicles could serve as dual therapeutic and diagnostic tools in precision ...

A new review in the Journal of Translational Medicine examines how cancer stem cells, vascularization and immune evasion contribute to ...

A preclinical study reports that combining the CD44v6 inhibitor AMC303 with the dual PI3K/mTOR inhibitor Apitolisib suppresses HGF-driven reprogramming and ...

A new review details how the immune checkpoint ligand PD-L1 doubles as a tumor-intrinsic driver of invasion through a reciprocal ...