Alcohol Drinking Patterns Leave Distinct Protein Fingerprints in Blood Plasma
A study of 47,514 UK Biobank participants found that plasma protein responses to alcohol differ by intake level, beverage type, ...
Tag: biomarkers
Speech-based machine learning detects Alzheimer’s across English and Greek cohorts
An acoustic-only machine-learning pipeline distinguished mild-to-moderate Alzheimer's disease from healthy controls with up to 90.4% mean accuracy across English and ...
Blood Gene Study Nominally Flags SLC51A and TPMT as Aneurysm Markers
An integrative analysis of blood transcriptomics and genetic data nominally prioritizes SLC51A and TPMT as exploratory candidate diagnostic genes for ...
AI pathology scoring flags longer survival on pembrolizumab in metastatic triple-negative breast cancer
An AI-based digital pathology assessment of PD-L1 identified metastatic triple-negative breast cancer patients with longer progression-free survival on pembrolizumab in ...
MRI diffusion and perfusion markers link MYD88/CD79B co-mutation to poorer outcomes in primary CNS lymphoma
A retrospective study of 92 patients found that quantitative diffusion and perfusion MRI parameters distinguished MYD88/CD79B co-mutated primary CNS lymphoma ...
Extracellular vesicles emerge as dual players and tools in cancer immunotherapy
A new review describes how tumor-derived exosomes suppress immunity while immune-cell-derived vesicles boost antitumor responses, highlighting exosome-based vaccines and biomarkers.
AI in MS, NMOSD, autoimmune encephalitis and MOGAD: promise still outruns proof
A new review finds AI applications in CNS autoimmune diseases are expanding rapidly, yet no model has been prospectively validated ...
MRI reveals nigrosome-1 neuromelanin and iron changes in Parkinson disease
Multimodal MRI shows that nigrosome-1 neuromelanin loss and iron changes, with inverted neuromelanin-iron coupling, best mark Parkinson's disease nigral degeneration.
Circulating tumor cells reveal immune escape tricks that may guide immunotherapy
A new review maps how circulating tumor cells survive immune attack in the bloodstream and outlines what evidence is still ...
Biosensors Move Cancer Detection Toward the Point of Care, Review Finds
A new review in Discover Sensors surveys how electrochemical, optical, microfluidic and nanomaterial biosensors are being engineered to detect cancer ...
Low antithrombin III flags organ failure risk in severe pancreatitis study
A retrospective cohort study found that among hypertriglyceridemia-associated acute pancreatitis patients with elevated D-dimer, those with reduced antithrombin III had ...
Acupuncture fMRI Findings Across the Alzheimer’s Continuum: What a Critical Review Reveals
A critical review of BOLD-fMRI studies finds acupuncture-related brain network changes across subjective cognitive decline, mild cognitive impairment, and Alzheimer's ...
Processed diets tied to gestational diabetes and altered blood proteins in Miao women
A matched case-control study of 78 Miao pregnant women in Guizhou, China, linked a processed dietary pattern to higher odds ...
Cell-free DNA liquid biopsy meets machine learning in cardiovascular disease review
A new review in Clinical Epigenetics outlines how cell-free DNA liquid biopsy and machine learning could be combined for cardiovascular ...
Biomarker model predicts severe amoebic liver abscess in Iraqi patients
An Iraqi study developed and internally validated a nomogram combining liver enzymes, inflammatory markers, and abscess characteristics to predict severe ...
HDAC isoform targeting offers a precision route to treating neurodegeneration
A new review argues that disease-specific HDAC isoforms, not broad-spectrum inhibition, should guide epigenetic drug development for neurodegenerative diseases.
Extracellular vesicles may reshape prostate cancer metabolism and its microenvironment
A new review describes how prostate cancer reverses its specialized citrate-producing metabolism and how extracellular vesicles may transfer metabolic signals ...
Flavoromics maps the volatile ticking clock of a stored wine cap mushroom
A flavoromics study tracked wine cap mushrooms over ten days of cold storage, detecting 9,746 volatile compounds and identifying eight ...
Gut Microbiome Gene Score Predicts Rheumatoid Arthritis Drug Response in New Study
A computational study built a gut microbiota–metabolite–host gene score that stratified rheumatoid arthritis patients into two molecular subtypes and predicted ...
Cancer therapies converge on shared heart injury pathways, prompting a dynamic surveillance framework
A new review introduces Cardio-Oncology Surveillance States, a conceptual framework that links shared biological injury pathways to risk-adapted cardiovascular monitoring ...
POPULAR NEWS
-
Scoping Review Maps Global Forensic Nursing Education Across Forty-Eight Studies
-
Comprehensive Survey Evaluates Emerging Architectures for Autonomous Driving Risk Assessment
-
3D Printing and Case-Based Learning Boost Orthopedic Sports Medicine Training Scores
-
Interprofessional Teams Tailor Multimodal Cancer Cachexia Care Through Iterative Clinical Assessment