Tag: Apoptosis

New research in Cell Division shows that Bcl-2 overexpression promotes survival of cutaneous squamous cell carcinoma cells by altering mitochondria-associated ...

A hydroxylated chalcone derivative called UR-2 suppressed the growth of CD133-positive lung cancer organoids by lowering Thioredoxin-2 expression and triggering ...

A new study reports that nanomolar GenX exposure reduces viability, triggers caspase-3- and PARP-associated apoptosis, raises ROS, and remodels 218 ...

A new cell culture study reports that combining doxorubicin with myo-inositol induced apoptosis in 25.12 percent of MCF7 breast cancer ...

A Mendelian randomization study combined with tumor database and cell experiments links genetically higher serum uric acid to lower gastric ...

A new mouse study shows that the RNA-binding protein hnRNPC supports cerebellar development by suppressing a cryptic exon in Mtf2 ...

Extracellular vesicles from the medicinal fungus Antrodia cinnamomea suppressed hepatocellular carcinoma cell proliferation, migration and invasion in laboratory assays, apparently ...

A new study reports that circ_0000745 attenuated renal and cellular injury endpoints in mouse and cell models of sepsis-induced acute ...

A new study finds that the transcription factor FOXA1 suppresses ferroptosis in cervical cancer cells by directly activating SLC7A11 transcription, ...

A laboratory study in immortalized human chondrocytes reports that high concentrations of metformin trigger caspase- and ROS-dependent apoptosis in senescent ...

A study links the transcription factor FOXO1 to chondrocyte proliferation, apoptosis and disease severity in developmental dysplasia of the hip.

A cell study finds that WTAP upregulates KDR through m6A modification, protecting human brain microvascular endothelial cells from angiotensin II-induced ...

Pterostilbene reduced inflammation, apoptosis, and oxidative DNA damage in rats with chemically induced ovarian insufficiency while strongly increasing SIRT1 and ...

A chitosan–PLA nanoformulation released plumbagin in a temperature-dependent manner and triggered apoptosis, autophagy and G2/M arrest in LPS-induced SiHa cervical ...

A rat study found that three weeks of ivermectin or hydroxychloroquine dosing caused oxidative stress, tissue damage and apoptosis markers ...

A combined network toxicology, molecular docking and in vitro study identifies ten shared genes and several pathways that may link ...

A review in Molecular Biology Reports describes how pro-inflammatory forms of regulated cell death, including ferroptosis, pyroptosis and necroptosis, contribute ...

A new study links VCAM-1 to colorectal cancer growth and spread through the RhoA/LIMK/Cofilin cytoskeletal pathway, while its survival association ...

A platinum(IV) prodrug covalently attached to mesoporous silica nanoparticles showed significantly greater cytotoxicity than cisplatin in patient-derived oral squamous cell ...

A new multi-omics study reports that myricetin from Myrica rubra binds HSP90AA1, suppresses PI3K–Akt signaling and inhibits bladder cancer growth ...