• HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
Sunday, August 3, 2025
BIOENGINEER.ORG
No Result
View All Result
  • Login
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
  • HOME
  • NEWS
  • EXPLORE
    • CAREER
      • Companies
      • Jobs
        • Lecturer
        • PhD Studentship
        • Postdoc
        • Research Assistant
    • EVENTS
    • iGEM
      • News
      • Team
    • PHOTOS
    • VIDEO
    • WIKI
  • BLOG
  • COMMUNITY
    • FACEBOOK
    • INSTAGRAM
    • TWITTER
No Result
View All Result
Bioengineer.org
No Result
View All Result
Home NEWS Science News Biology

Entos and Precision NanoSystems partner to enable GMP manufacturing of DNA COVID-19 vaccine

Bioengineer by Bioengineer
May 7, 2020
in Biology
Reading Time: 3 mins read
0
Share on FacebookShare on TwitterShare on LinkedinShare on RedditShare on Telegram

Entos Pharmaceuticals partners with Precision Nanosystems to enable highly scalable GMP manufacturing of Fusogenix DNA COVID-19 vaccine and other genetic nanomedicines

IMAGE

Credit: Precision NanoSystems Inc.

EDMONTON, Alberta, May 7, 2020 — Entos Pharmaceuticals (Entos), a healthcare biotechnology company developing next generation nucleic acid medicines with their Fusogenix delivery platform announced today a partnership with Precision NanoSystems, Inc., (PNI), a global leader in enabling transformative nanomedicines, to produce clinical grade vaccines and therapeutics using PNI’s NanoAssemblr™ GMP System.

Entos develops next generation nucleic acid-based therapies using the proprietary Fusogenix drug delivery system, a proteo-lipid vehicle (PLV) that delivers molecules, intact and unmodified, directly into the cytosol of target cells. Entos has recently launched a DNA vaccine rapid prototyping project around the development of a pan-coronavirus DNA vaccine, with the aim of broad availability within one year. To reach this ambitious target, Entos will incorporate PNI’s NanoAssemblr GMP System into the manufacturing suite at the Alberta Cell Therapy Manufacturing (ACTM) Facility, located in the University of Alberta’s Li Ka Shing Centre for Health Research Innovation. This will enable the production of clinical grade Fusogenix genetic nanomedicines such as Covigenix, Entos’s pan-coronavirus Fusogenix DNA vaccine.

James Taylor, Co-Founder and CEO of PNI said, “We’re excited to rapidly deploy our NanoAssemblr GMP System and NxGen microfluidic technology at ACTM for Entos to scale up and manufacture their DNA vaccine against COVID-19 using their drug delivery system.”

“PNI is globally renowned for their NanoAssembr suite of products that enable high quality, consistent nanoparticle formation and seamless scale up from the laboratory to GMP manufacturing for the clinic,” said Dr. John Lewis, CEO of Entos, “using their GMP System will let us meet the challenge of producing our pan-coronavirus DNA vaccine at large scale and in as short a time as possible, while exceeding all safety and quality requirements.”

PNI’s proprietary NanoAssemblr GMP System is a modular solution to enable rapid deployment and configuration to meet the requirements at each scale of clinical manufacturing. PNI’s Clinical Solutions team will perform technology transfer of the GMP System to ACTM and support accelerating Entos’ COVID-19 vaccines and therapeutics, significantly reducing the time needed to deliver these needed programs to the public.

###

About Entos Pharmaceuticals, Inc.

Entos develops next generation nucleic acid-based therapies using their proprietary Fusogenix drug delivery system. Fusogenix is a proteo-lipid vehicle (PLV) formulation that uses a novel mechanism of action to deliver molecules, intact and unmodified, directly into the cytosol of target cells. The technology is applicable to a wide range of therapeutic types including gene therapy, mRNA, miRNA, RNAi, CRISPR and small molecule drugs. For more information visit http://www.entospharma.com.

About Precision NanoSystems Inc.

Precision NanoSystems Inc. (PNI) proprietary NanoAssemblr Platform enables the rapid, reproducible, and scalable manufacture of next generation nanoparticle formulations for the targeted delivery of therapeutic and diagnostic agents to cells and tissues in the body. PNI provides instruments, reagents and services to life sciences researchers, including pharmaceutical companies, and builds strategic collaborations to revolutionize healthcare through nanotechnology. For more information visit http://www.precisionnanosystems.com.

For more information regarding this press release, contact:

John D. Lewis, Ph.D.

CEO, Entos Pharmaceuticals, Inc.

Phone: (780) 862-7445

Email: [email protected]

Media Contact
John Lewis
[email protected]

Tags: Biomedical/Environmental/Chemical EngineeringBiotechnologyImmunology/Allergies/AsthmaInfectious/Emerging DiseasesMedicine/HealthPharmaceutical ScienceResearch/DevelopmentVaccinesVirology
Share12Tweet8Share2ShareShareShare2

Related Posts

blank

CK2–PRC2 Signal Drives Plant Cold Memory Epigenetics

August 2, 2025
blank

AI-Driven Protein Design Advances T-Cell Immunotherapy Breakthroughs

August 1, 2025

Melanthiaceae Genomes Reveal Giant Genome Evolution Secrets

August 1, 2025

“Shore Wars: New Study Tackles Oyster-Mangrove Conflicts to Boost Coastal Restoration”

August 1, 2025
Please login to join discussion

POPULAR NEWS

  • Blind to the Burn

    Overlooked Dangers: Debunking Common Myths About Skin Cancer Risk in the U.S.

    60 shares
    Share 24 Tweet 15
  • Neuropsychiatric Risks Linked to COVID-19 Revealed

    51 shares
    Share 20 Tweet 13
  • Dr. Miriam Merad Honored with French Knighthood for Groundbreaking Contributions to Science and Medicine

    46 shares
    Share 18 Tweet 12
  • Study Reveals Beta-HPV Directly Causes Skin Cancer in Immunocompromised Individuals

    38 shares
    Share 15 Tweet 10

About

We bring you the latest biotechnology news from best research centers and universities around the world. Check our website.

Follow us

Recent News

Nano- and Micro-Polystyrene Impact Gut Cells, Neurons

Adolescents Face Cancer’s Impact on Identity, Sexuality

Critical 70% CO2 Threshold for Viable Geological Storage

  • Contact Us

Bioengineer.org © Copyright 2023 All Rights Reserved.

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
No Result
View All Result
  • Homepages
    • Home Page 1
    • Home Page 2
  • News
  • National
  • Business
  • Health
  • Lifestyle
  • Science

Bioengineer.org © Copyright 2023 All Rights Reserved.