Cancer

A large EBMT registry analysis of 3385 adults with AML in remission and measurable residual disease found that haploidentical transplantation...

A bibliometric analysis of 5,967 publications maps a decade of MDSC research, identifying leading countries, institutions, authors, and emerging research...

A new clinical mini-review proposes an evidence-informed framework for deciding which bladder cancer patients should be evaluated for previously unrecognized...

A conference correspondence summarizing 12 clinical and translational abstracts on next-generation CAR-T therapy for malignant brain tumors, reporting early feasibility...

The DSEE-CRC trial will randomize patients with chemotherapy-refractory metastatic colorectal cancer to tumoroid-guided therapy or standard trifluridine-tipiracil and bevacizumab.

Researchers identified a POSTN-expressing tumor-associated endothelial cell subset that promotes and predicts pulmonary metastasis in osteosarcoma.

BRAF inhibitor-resistant melanoma cells release M-CSF and remodel the immune microenvironment, and blocking this signal improved drug efficacy in mouse...

A rat study found that biological sex modified both radiation-induced lung injury patterns and the effectiveness of enalapril, metformin and...

A new review shows likelihood ratios reveal wide variability in how well palliative prognostic tools discriminate short-term mortality.

A retrospective study of 125 advanced sarcoma patients found molecular tumor board recommendations led to treatment in 32.8 percent, with...

A retrospective single-center study of 75 treatment-naive CLL/SLL patients reports an 86.7% response rate with frontline orelabrutinib monotherapy and no...

A large prospective Children's Oncology Group trial found that cancer-free surgical margins as narrow as one millimeter were associated with...

A spatial transcriptomics study links depletion of non-tumoral B cells to relapse risk in classical Hodgkin lymphoma and introduces an...

Extracellular vesicles from the medicinal fungus Antrodia cinnamomea suppressed hepatocellular carcinoma cell proliferation, migration and invasion in laboratory assays, apparently...

Adapting to serine and glycine scarcity rewires mitochondrial metabolism in pancreatic cancer cells and increases their cancer stem cell frequency,...

The phase III MAVERICK trial found that brain MRI surveillance without prophylactic cranial irradiation improved cognitive failure-free survival and caused...

A nationwide Danish study presented at the EASD annual meeting found cancer incidence was 12% higher in men and 22%...

An AI-based digital pathology assessment of PD-L1 identified metastatic triple-negative breast cancer patients with longer progression-free survival on pembrolizumab in...

A Nature Reviews Cancer review argues that theranostics should expand beyond radiolabelled peptides to include nanotheranostics, microtheranostics and imaging-guided surgery.

A new study reports that combining the multi-target kinase inhibitor cediranib with KRASG12C inhibitors overcomes resistance by sustaining ERK blockade,...