Cancer

A multi-institutional retrospective cohort study found that autologous breast reconstruction was associated with lower reconstruction failure and better physician-assessed cosmesis...

A CEA-coated PLLA–ZnO nanowire nano-vaccine elicited balanced Th1/Th2 immunity and reduced tumor growth by 65–70% in a prophylactic mouse model.

Researchers in Singapore propose a multidisciplinary institutional protocol for diagnosing and treating rare primary cardiac sarcomas, illustrated by two left...

A retrospective study of 92 patients found that quantitative diffusion and perfusion MRI parameters distinguished MYD88/CD79B co-mutated primary CNS lymphoma...

A Taiwanese case report documents 21-month survival after leptomeningeal metastasis in a rare triple-negative breast cancer subtype treated with sacituzumab...

A combination of low-dose metformin and valproic acid reprograms the metabolism of drug-tolerant persister cells in gastric and liver cancer...

A new study reports that the m6A reader protein IGF2BP3 promotes non-small cell lung cancer progression by stabilizing TROAP mRNA...

A pan-cancer analysis of 8136 TCGA patients found no consistent survival association for functionally prioritized synonymous mutations, though selected cancer-specific...

A new review details how the pan-RAS inhibitor daraxonrasib doubled overall survival in a phase III pancreatic cancer trial and...

Researchers engineered GE11-targeted vesicles that delivered tumor-suppressive miR-204 into EGFR1-positive triple-negative breast cancer cells, inhibiting their growth in lab and...

A meta-analysis of 34 studies links cancer cachexia to higher odds of postoperative complications and longer hospital stays in gastrointestinal...

A case report documents four metachronous neoplasms in one MSH2 mutation carrier over eight years, with only the endometrial cancer...

A new Cellular Oncology study reports that the tumor suppressor TNFAIP3 restrains lactylation-linked DNA damage repair and increases ovarian cancer...

A lab coculture study found that adding neutrophils increased mitochondrial activity in a triple-negative breast cancer and fibroblast model.

A mouse study finds that acclimatization to 3,466 m hypobaric hypoxia suppresses hepatic bile acid metabolism and remodels tumor lipids...

A retrospective analysis of ten rare SWI/SNF-deficient sinonasal carcinomas documents diverse morphology, nine SMARCB1-deficient and one SMARCA4-deficient case, three recurrences...

A population-based study of 325 nonmetastatic soft tissue sarcoma cases in the Veneto region found five-year overall survival of 73.2%,...

A new review maps how natural active compounds can self-assemble into carrier-free nanostructures for cancer therapy, while flagging major translational...

Preclinical work shows the pan-RAS inhibitor RMC-6236 triggers adaptive EGFR feedback in KRAS-mutant cholangiocarcinoma cells, and pairing it with cetuximab...

A systematic review and meta-analysis finds salivary nucleic acid biomarkers, especially in integrated validation-phase models, show promising but not yet...