Cancer

A mouse study in The Journal of Immunology reports that hyperglycemia reprograms T cells through an IGF1-IGF1R signaling pathway to...

A prospective cohort study of 91 laparoscopic colorectal cancer surgery patients found that a 14.5 percent or greater reduction in...

A multi-phase MRI deep learning model combined with clinical predictors differentiated hepatocellular carcinoma from mass-forming intrahepatic cholangiocarcinoma with AUCs of...

A post-hoc safety analysis of the phase 3 OptiTROP-Breast01 trial found that sacituzumab tirumotecan's key adverse events arose mainly in...

A new review maps how a self-reinforcing platelet-neutrophil immunothrombotic circuit builds a pre-metastatic lung niche in breast cancer and evaluates...

In a two-centre exploratory study of 117 clear-cell renal cell carcinoma patients, 43.5% of recurrences within 24 months occurred among...

A multicenter retrospective study reports that a fusion model combining MRI habitat radiomics, Vision Transformer deep learning features and clinical...

Heart muscle cells grown from lung cancer patients reproduce individual susceptibility to osimertinib-induced cardiac dysfunction, with impaired AMPK–LKB1 signaling marking...

Hyaluronic acid-modified taurine-polydopamine nanoparticles combined photothermal therapy with taurine-driven immune modulation to suppress gastric tumors in mice.

A new study reports that lactate in the pancreatic tumor microenvironment promotes metabolic reprogramming and PD-L1 upregulation through the TRMT6-SIRT5...

A German multicentre survey of 120 hospital physicians finds wide disagreement among cardiologists and internists on LVEF thresholds, strain imaging...

A prospective questionnaire study found readers rated LLM-structured oncologic CT reports higher than free-text reports on 11 of 12 items,...

A new review finds edible source-derived exosome-like nanoparticles show preclinical promise against hepatocellular carcinoma, but clinical translation faces major hurdles.

A prospective pilot study of 21 stage III NSCLC patients found that serum extracellular vesicle–enriched miR-21 significantly decreased after chemoradiotherapy,...

A new review describes how the long non-coding RNA MALAT1 drives leukemia cell survival, proliferation and chemotherapy resistance in acute...

A new Cellular Oncology study shows that the enzyme PLA2G2A drives gallbladder cancer progression by promoting cancer stemness through PLA2R1,...

A screen of over 1400 FDA-approved compounds identified topoisomerase I inhibitors as the most effective partners for PARP inhibitors in...

A new Cellular Oncology study reports that short-term starvation suppresses colorectal cancer cells by upregulating IRF7, which downregulates PFKFB3, induces...

A multimodal AI model built from routine pathology slides predicts bladder cancer survival and led researchers to RTN3, which drives...

A new narrative review maps how evidence-based glioblastoma care can be delivered across resource-variable health systems in Mexico and Latin...