Cancer
Male and female breast cancer patients in India show distinct clinical and psychosocial profiles
A cross-sectional study of 355 breast cancer patients at two Indian cancer hospitals found that women reported higher symptom severity...
Frontiers Retracts Corrigendum on ABTL0812 in Glioblastoma Over Image Concerns
Frontiers in Oncology has retracted a 2025 corrigendum on the anticancer effects of ABTL0812 in glioblastoma models after the authors...
Positive attitudes toward physical activity tied to well-being in cancer patients
A German cross-sectional study of 316 cancer patients found that positive attitudes and expectations toward physical activity, but not self-reported...
Experimental Compounds Curb Glioblastoma Cell Invasion in Tissue Slice Models
In ex vivo xenograft tissue slice co-cultures, indole analogs and the aryl sulfonamide AqB011 potently inhibited glioblastoma cell invasion into...
Long noncoding RNA MANCR drives glioblastoma growth via miR-205-5p and CASP3
A new study finds that the long noncoding RNA MANCR is elevated in glioblastoma and promotes tumor growth and invasion...
Physical Limitations Shape How Hospitalized Cancer Patients Judge Their Care
A cross-sectional study of 239 hospitalized oncology patients found that functional care needs explained about 10.9 percent of the variance...
When scans and blood tests disagree, AI could help oncologists decide what to do next
A new narrative review proposes a five-dimensional taxonomy for disagreements between imaging and circulating tumor DNA testing and frames multimodal...
Bladder cancer immune landscape is compartmentalized, treatment-modified, and context dependent
A new narrative review finds that the clinical meaning of immune infiltration in bladder cancer depends on cell localization, functional...
Gut microbes may decide who responds to lung cancer immunotherapy
A new review maps how gut bacteria and their metabolites remotely reprogram lung tumors to shape immunotherapy response, resistance and...
CAR-T Cytokine Release Syndrome Shows Distinct Symptom Profiles by Timing, Severity and Duration
A retrospective study of 128 multiple myeloma patients links distinct CRS symptom profiles to onset timing, severity and duration after...
Hong Kong Team Makes CAR-T Therapy for Children With Leukaemia in Just 14 Days
A Hong Kong phase II trial of six children found that locally manufactured point-of-care CD19 CAR-T cells, produced in 14...
Hearing checks should be standard care for every child on cisplatin, experts urge
A German-Indonesian expert working group argues that baseline and end-of-treatment hearing assessments should be mandated for every child receiving cisplatin...
Precision Brachytherapy Improves Dosimetry in Salvage Treatment for Recurrent Gynecologic Cancers
A retrospective study analyzed 27 patients treated with transvaginal HDR-ISBT for centrally recurrent pelvic gynecologic malignancies, finding that 3D-PT-assisted implantation...
RNA Modifications and Metabolism: Decoding Crosstalk in Liver Cancer
RNA modification networks and metabolic reprogramming establish reciprocal circuits that drive hepatocellular carcinoma progression and therapeutic resistance.
Artemisinin May Curb Gastric Cancer Cells by Damping ERK Signaling
A new in vitro study reports that artemisinin suppresses gastric cancer cell proliferation, migration, and invasion while reducing ERK/MAPK pathway...
Rare MSH2 Variant Linked to Three Cancers in One Lynch Syndrome Patient
A Frontiers in Oncology case report documents a 62-year-old woman carrying the known pathogenic MSH2 p.A230Lfs*16 germline variant who developed...
THOR hypermethylation drives hTERT reactivation in cervical cancer
A study of Indian cervical cancer patients links THOR hypermethylation to hTERT reactivation and reduced menin recruitment, independent of HPV...
Palliative Sedation Often Follows a Cascade of Refractory Symptoms, Not a Single One
An international observational study of 80 advanced cancer patients finds that palliative sedation is typically prompted by multiple interacting refractory...
Pembrolizumab Brings Heavy Toxicity Burden for Older Breast Cancer Patients in Real-World Care
A real-world cohort study of 136 patients aged 65 and older found high rates of hospitalization and immune-related toxicity with...
STAM protein suppresses kidney cancer through a dual EGFR and AKT mechanism
New preclinical research shows the STAM protein suppresses clear cell renal cell carcinoma by inactivating EGFR and degrading AKT, inducing...
POPULAR NEWS
-
Physicists control the magnetic nucleus of a single atom with radio waves
-
Long Noncoding RNA SNHG4 Emerges as a Player Across Multiple Human Cancers
-
Bladder Artery Embolization Before Tumor Resection Cuts Bleeding and Surgery Time
-
Vial surface treatment and early creeping predict fogging in freeze-dried drugs