Cancer

A randomized phase III trial found better cognitive failure–free survival with brain MRI surveillance alone than with surveillance plus cranial...

A retrospective study of 8,595 thyroid fine-needle aspirations found that higher Bethesda categories were associated with aggressive surgical pathology, particular...

A preclinical study reports that the IL-13E13Y-based T-cell engager 313TE linked IL-13Rα2-positive tumor cells to T cells, promoting receptor-dependent killing...

A retrospective single-center study of 447 patients found that a model integrating glypican-3 with clinical features predicted overall and time-specific...

A scoping review of 17 lifestyle interventions for adolescent and young adult childhood cancer survivors found that physical activity dominates...

A first small clinical study found encouraging tumor control, symptom relief and tolerability with minibeam radiotherapy in 36 patients with...

A patient-derived colon cancer liver-metastasis cell line, CRC-X1, was stably passaged through 59 generations, formed tumors in 60% of mouse...

A retrospective Nepalese cohort of 31 patients associated 20- or 40-milligram nivolumab with responses across advanced cancers, but uncontrolled evidence...

An observational study of 3.3 million research participants found that inherited EGFR T790M was associated with 25-fold higher lung cancer...

An exploratory diagnostic study found that combining Trx1 and CA125 produced higher reported ovarian cancer sensitivity than ROMA overall, in...

A peer-reviewed review identifies altered lipid uptake, synthesis, oxidation and storage as drivers of hepatocellular carcinoma and possible therapeutic targets,...

A retrospective cohort of 2,278 chemotherapy-treated gastrointestinal cancer patients found that 88.1% visited an emergency department and 86.5% were admitted...

An Ontario cohort study linked greater neighborhood material deprivation with 36.2 fewer adjusted days at home during the first year...

A systematic review of 77 articles found consistent evidence for supervised physical activity improving strength and exercise capacity during childhood...

A review of 972 patients found that histotripsy had low laboratory toxicity and procedural complication rates, while 11% died within...

A systematic review of 200 publications found the clearest clinical evidence for tyrosine kinase inhibitors in canine mast cell tumours,...

A 2026 review finds that TCR-engineered T cells have entered early clinical testing for hepatocellular carcinoma, but safety, antigen heterogeneity...

A 2026 commentary proposes classifying tumors as innate, acquired or combined-etiology while describing the framework and its therapeutic implications as...

A qualitative study of 18 patients with head and neck cancer found that swallowing-exercise adherence involved interactions between habitual cues,...

A planned 90-patient randomized trial will compare cilastatin with sodium thiosulfate for preventing acute kidney injury during cisplatin-based HIPEC, but...