Cancer

An iron-engineered mesoporous organosilica nanoplatform improved delivery of the natural compound DMDD and inhibited breast tumor growth in preclinical models...

A new study shows that the stress sensors ATF4 and ATF6 coordinate transcriptional and metabolic responses to glucose deprivation in...

A new Cancer Imaging editorial argues that volumetric nodule measurement and volume doubling time outperform diameter-based assessment in lung cancer...

A pre-immunotherapy MIBG Curie score above 3 independently predicts poorer progression-free survival in children with high-risk neuroblastoma receiving anti-GD2 immunotherapy.

Hyaluronic acid-decorated, iron oxide-loaded PLGA nanoparticles guided by a pulsed electromagnetic field increased tumor accumulation of doxorubicin roughly 1.5-fold in...

A preclinical study reports that the MEK inhibitor cobimetinib suppressed MAPK signaling, tumor cell invasion and immune-evasive features in anaplastic...

A study of breast tissue microarrays mapped where regulatory RNAs and stromal proteins sit within benign, DCIS and invasive lesions,...

A narrative review maps short- and long-term cardiovascular complications after hematopoietic stem cell transplantation and endorses the CARE-BMT score for...

A review in Discover Oncology describes how the gut microbiota can modulate chemotherapy efficacy and resistance through drug sequestration, metabolic...

A UK retrospective cohort study of 133 patients with loco-regional recurrent melanoma found surgery was the predominant treatment, with immunotherapy...

A SEER analysis of 21,492 hepatocellular carcinoma patients shows the prognostic impact of AJCC stage wanes over time, with five-year...

A new review maps how calreticulin and its fragments can both promote and suppress tumors depending on context.

A retrospective study of 83 men with metastatic hormone-sensitive prostate cancer found that Hispanic American patients presented with more advanced...

A UK-wide analysis of almost 16,000 IBD surveillance procedures found that endoscopist experience, procedure time and dye use were associated...

A computational study combined gene co-expression network analysis and machine learning to nominate twelve candidate biomarkers for malignant pleural mesothelioma,...

A retrospective two-center study found an FDA-cleared AI tool classified 60.6 percent of benign BI-RADS 4 breast lesions as probably...

A University of Texas at San Antonio and National Cancer Institute study of 42,571 Texas women found the state's highest...

A new ASTRO clinical guideline recommends moderately shortened radiation schedules for all risk groups of localized prostate cancer and establishes...

Researchers report an immune-enhanced boron neutron capture therapy platform that achieved high intratumor boron-10 levels and a model-estimated 99.6 percent...

A study of 44 children found that MAP and NODDI diffusion metrics matched DWI in grading pediatric intracranial tumors, with...