Biology
How Co-Transcriptional Splicing Is Detected, Regulated, and Harnessed for Therapy
Co-transcriptional splicing, once viewed primarily as a routine step in messenger RNA production, is emerging as a central regulator of...
Roadkill may push shrinking hedgehog populations toward collapse, study warns
Road traffic may be pushing Britain’s smallest hedgehog populations toward collapse, according to a new study showing that even one...
Cooperation May Hold the Key to Reproductive Success
Fertilization is usually portrayed as a microscopic race: millions of sperm cells competing to reach a single egg, with only...
New informatics tools transform biodiversity data into actionable policy insights
Biodiversity data are accumulating at an extraordinary rate, yet the information needed to understand ecological change often remains fragmented, inconsistent,...
New discovery may help microbes withstand harsh industrial processes
Fluoride is usually discussed in the context of toothpaste, drinking water, or industrial pollution. At the cellular level, however, it...
New genetic tool reveals how genes are regulated
The human genome contains more than 20,000 genes, yet most cells use only a fraction of them at any given...
Scientists reveal how muscles preserve cells responsible for repair
A protein famous for safeguarding the protective caps at the ends of chromosomes has been found to play a far...
Extracellular Vesicles May Help Weather Cytokine Storms
A specially engineered cell-derived therapy may offer a new way to control the dangerous inflammation associated with cytokine storms, according...
Insilico Medicine launches the industry’s first Drug Discovery and Development (DDD) benchmark as a service, to evaluate frontier AI and foundation models on real-world science
image: Leveraging 30+ validated PCC programs and over 12 years of model development experience to create a large-scale real-world “blind test”...
Cemiplimab and fianlimab with neoadjuvant chemotherapy in early-stage high-risk -negative breast cancer
About the Study: Is combined inhibition of programmed cell death 1 protein (PD-1) and lymphocyte activation gene 3 (LAG-3) added...
Combined phage therapy and faecal microbiota transplantation to treat recurrent urinary tract infection: a case series
McCallin, S., Classen, A.Y., Lieberknecht-Jouy, S.C. et al. Combined phage therapy and faecal microbiota transplantation to treat recurrent urinary tract...
Essential genetic mutations impair DNA damage repair and modulate tumor immune microenvironment in ccRCC
image: Role of VHL in DDR. view more Credit: HIGHER EDUCATION PRESS Clear cell renal cell carcinoma represents one of...
Microbiota-derived 10-hydroxystearic acid activates PPARα to restore gut epithelial barrier integrity and enhance anti-retroviral therapy
Kramer, D., Santos Rocha, C., Gaulke, C.A. et al. Microbiota-derived 10-hydroxystearic acid activates PPARα to restore gut epithelial barrier integrity...
Amazonian ‘zombie’ fungus harbors a hidden stage inside forest mosses, new study reveals
image: Camponotus nidulans ants infected by O. camponoti-nidulantis found among bryophytes at the Adolpho Ducke Forest Reserve. Specimen “TAJ59” found on...
Shining a light on constructing blood supply systems for artificial tissues
video: Concept of meniscus-guided interfacial ring-by-ring assembly for in situ fabrication of tubular hydrogels view more Credit: 2026, Yuki Kamiya et...
LorMe: a unified framework for standardized microbiome analysis
image: Overview of the analytical workflow implemented in LorMe view more Credit: Ningqi Wang, Yaozhong Zhang, Xinrui Yangon, et al. Microbial...
Beyond bunny tourism: the hidden consequences of unregulated feeding of rabbits on Okunoshima Island
image: The illustration depicts an unusual event observed on Okunoshima Island, where wild boars have been seen capturing rabbits. Researchers suggest...
Chicken kidney sponge could be ‘outstanding’ at cleaning up polluted ports
image: Specimen of the chicken kidney sponge Chondrosia reniformis transplanted into the harbor view more Credit: Carlota Escarré Ports rank among the...
Why the hepatitis E virus cannot infect mice
Genetic material is not unpacked It has long been known that the hepatitis E virus cannot establish an infection in...
Biofilm clue opens route to anti-infection treatments of the future
image: BatR contributes to biofilm architecture (purple) on pig lung tissue (pink). Images are shown here for stained tissues treated with Ciprofloxacin. Pseudomonas aeruginosa biofilm...