NLRP3 Deficiency Eases Colitis by Preserving Gut Bacteria That Make Short-Chain Fatty Acids
Deleting the NLRP3 inflammasome gene in mice eased colitis while preserving short-chain fatty acid-producing gut bacteria, and a probiotic lost ...
Deleting the NLRP3 inflammasome gene in mice eased colitis while preserving short-chain fatty acid-producing gut bacteria, and a probiotic lost ...
A new review synthesizes preclinical evidence that traditional Chinese medicine monomers and decoctions can rebalance Th17-driven immune responses in ulcerative ...
A Limosilactobacillus reuteri strain isolated from Hu lambs ameliorated DSS-induced colitis in mice when given prophylactically, by modulating gut microbiota, ...
A Mendelian randomization and transcriptomic study identified 11 gut microbial taxa genetically associated with ulcerative colitis and nominated PHLPP2 and ...
Machine learning models using gut microbial virulence factor profiles classified inflammatory bowel disease with up to 90.17% accuracy in an ...
A prospective Italian cohort of 113 patients with inflammatory bowel disease found that confirmed sarcopenia was independently associated with IBD-related ...
A UK-wide analysis of almost 16,000 IBD surveillance procedures found that endoscopist experience, procedure time and dye use were associated ...
A retrospective analysis of Italian administrative databases covering about four million people estimates that ulcerative colitis affected roughly 160,000 Italians ...
A retrospective multicenter study in China found fecal calprotectin was documented in only 0.9 percent of 655 patients, prompting a ...
A five-year NIH-funded Mount Sinai study will examine associations between PFAS exposure, pre-diagnostic glycosylation changes and later inflammatory bowel disease ...
An observational study found hidden immune activity and a distinctive gut environment in bowel disease associated with PSC, offering a ...
An integrative reanalysis of 778 baseline mucosal transcriptomes from public ulcerative colitis cohorts identified three gene-expression endotypes that stratify healing ...
A review finds that protein modifications regulate immune inflammation and epithelial barrier dysfunction in ulcerative colitis through mechanisms that remain ...
A preclinical mouse study found that intraperitoneally delivered macrophages engineered to secrete IL-10 reduced disease activity, preserved colon length, and ...
A critical review finds preliminary short-term efficacy signals and biologically coherent mechanisms for a Chinese five-material colon-targeted capsule in ulcerative ...
A macrophage-targeted TIMD4 peptide nanoparticle reduced inflammation and monocyte recruitment in a mouse colitis model without establishing clinical benefit in ...
A 2026 review finds that several natural compounds alter PPARγ-related pathways in cellular and mouse models of ulcerative colitis, but ...
A large-scale serology study presented at UEG Week 2026 found distinct antibody signatures up to ten years before an inflammatory ...
A new case report details how ulcerative colitis, chronic steroid therapy, undetected osteoporosis, immobilization, and spinal surgery combined to trigger ...
A new special issue in Frontiers in Pediatrics gathers ten peer-reviewed studies revealing how inflammatory bowel disease presents, is diagnosed, ...
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