Tag: tumor microenvironment

A retrospective study of 83 men with metastatic hormone-sensitive prostate cancer found that Hispanic American patients presented with more advanced ...

A new review finds that CT-derived extracellular volume fraction correlates with fibrosis, tumor biology, prognosis, and treatment response across abdominal ...

A machine learning model built from single-cell data stratifies osteosarcoma patients by survival risk and identifies OPN3 as a candidate ...

Preclinical research shows that blocking the aryl hydrocarbon receptor reshapes myeloid–T cell crosstalk and enhances anti-PD-1 responses across mouse and ...

Researchers identified PLPP4 as a functional marker of an ECM-enriched cancer-associated fibroblast subset that promotes tumor growth and metastasis via ...

Single-cell and multi-omics analyses of hepatocellular carcinoma point to IL-1β-positive macrophages and IL-1R1-positive inflammatory fibroblasts as putative drivers of a ...

A narrative review argues that the acidic tumor microenvironment suppresses antitumor immunity and that targeting acidity is a preclinically supported ...

A retrospective Chinese study reports that all 11 patients with lymph-node-dominant metastatic gallbladder cancer responded to PD-1 blockade plus gemcitabine ...

VIB-KU Leuven researchers report that blocking lipid signals from brain immune cells made glioblastoma less invasive in mouse models and ...

A Science Bulletin review outlines how multimodal artificial intelligence integrating molecular, cellular, and clinical data could refine immunotherapy decisions while ...

A new review outlines how the copper-dependent cell death regulator FDX1 may shape prognosis, metabolism, and treatment resistance in triple-negative ...

A multi-omics study of 63 colorectal tumors links higher bacterial richness, specific anaerobic taxa, myeloid immune infiltration and the metabolite ...

A new study identifies the CXCL1/8-CXCR1/2 chemokine axis as a driver of the inflammatory tumor microenvironment and matrix remodeling in ...

A new review in Medical Oncology examines marine microbial arginase as a stable enzyme platform for arginine deprivation therapy against ...

A BMC Medicine debate article argues that T cells in acute myeloid leukemia are not uniformly dysfunctional and that assessing ...

A new review describes how tumors reprogram Schwann cells into states linked to perineural invasion, matrix remodeling and altered immune-cell ...

A recombinant overlapping peptide vaccine targeting HPV16 E7, combined with 4-1BB agonist antibody, eradicated established tumors in most treated mice ...

A new review maps how gut bacteria and their metabolites remotely reprogram lung tumors to shape immunotherapy response, resistance and ...

A new review maps how biomaterials can exploit cholesterol metabolism in cancer while warning that most mechanistic claims remain unproven.

A new review in the Journal of Translational Medicine examines how cancer stem cells, vascularization and immune evasion contribute to ...