From Mild to Severe Hypoxia: How HIF-1α Orchestrates the Tumor Cells’ Survival Symphony
In the dynamic landscape of cellular biology, oxygen availability stands as a fundamental determinant of cell fate, survival, and function. ...
Tag: tumor microenvironment
CD2AP Alters Tumor Microenvironment, Boosts Immunotherapy
In the relentless pursuit of combating gastric cancer, a disease notorious for its high mortality and global prevalence, new molecular ...
Exosome-Driven Ferroptosis: Tumor Insights to Therapies
A rapidly evolving frontier in cancer biology reveals the profound influence of exosomes on the tumor microenvironment (TME), particularly through ...
AAV-CRISPR Targets PD-L1 for Ovarian Cancer
In a groundbreaking advancement in ovarian cancer therapeutics, researchers have unveiled a pioneering gene immunotherapy approach leveraging adeno-associated virus (AAV) ...
G-CSF-Mediated Metastatic Niche Development in the Omentum
The omentum is a common site of metastasis for many cancers originating from organs in the abdominal cavity, particularly epithelial ...
Moffitt Research Reveals Potential of Vaccine to Enhance Breast Cancer Treatment Efficacy
A Breakthrough in Breast Cancer Immunotherapy: Moffitt Cancer Center’s Vaccine Strategy At the forefront of cancer treatment innovation, researchers at ...
Distinct Cellular Populations Uncovered in the Transcriptional Landscape of Pancreatic Ductal Adenocarcinoma
Pancreatic cancer remains a formidable adversary in the realm of oncology, characterized by its stealthy progression and dire prognosis. Among ...
Cancer Hijacks Mitochondria to Paralyze Immune Attack
In a dramatic revelation that challenges conventional thinking about cell biology, scientists report that cancer cells can effectively “poison” the ...
