Blood gene signature flags severe pancreatitis with near-perfect accuracy
A five-gene blood panel built from neutrophil-driven transcriptomic signatures classified severe acute pancreatitis with an AUC of 0.890 against milder ...
Tag: RNA-Seq
New SHAKIRA Pipeline Estimates Genetic Ancestry Directly from RNA-seq Data
A new pipeline called SHAKIRA estimates broad genetic ancestry from cancer RNA-seq data, showing strong concordance with DNA-based estimates in ...
Grapevine transcriptome atlas maps RNA diversity in developing clusters under gibberellin
An open RNA-seq dataset from gibberellin-treated and control Sistan Yaghooti grape clusters catalogs alternative splicing events, long non-coding RNAs and ...
Green sanitizer drives Listeria into a hidden viable but nonculturable state
RNA sequencing reveals that a gallic acid-based green sanitizer drives Listeria innocua into a viable but nonculturable state marked by ...
New Python package opens the recount3 RNA-seq data trove to machine learning workflows
A new Python package provides programmatic access to tens of thousands of uniformly processed RNA-seq samples from human and mouse ...
Wheat Drought Tolerance Genes Revealed by Combined GWAS and RNA-Seq Study
A combined GWAS and RNA-Seq study of 257 Chinese spring wheat lines identified 20 drought-response loci and seven candidate genes, ...
Research report: Transcriptome datasets of four freshwater bacterial isolates grown under iron-replete and iron-limited conditions
An open RNA-seq dataset from four freshwater bacterial isolates grown with and without iron documents 349,853,404 processed reads for comparative ...
Small neural network sharpens gene alignment across species
A compact deep-learning model called minisplice learns splice signals across vertebrates and insects and, when integrated into minimap2 and miniprot, ...
New tool prunes misleading redundant pathways from gene enrichment results
PathwayDenester re-evaluates enriched pathways by testing whether their significance depends on overlapping, more significant terms, filtering out 40 to 90 ...
Silicon Transporter Gene Lsi1 Linked to Bacterial Salinity Relief in Rice
Transcriptome network analysis and physiological experiments converge on the silicon transporter gene Lsi1 as a candidate gene in rice responses ...
Maternal BMI Leaves Distinct Molecular Fingerprints in Placenta, Mother and Fetus
An exploratory multi-compartment study found that higher third-trimester maternal BMI is associated with distinct gene-expression and pathway signatures in maternal ...
Research report: Whole-genome sequencing of CRFK and PG-4 cells to infer the phenotype of the original donor cats
Whole-genome sequencing of the CRFK and PG-4 feline cell lines has allowed researchers to infer that one donor cat had ...
AI pathology model stratifies glioma patient risk across 2,552 cases
A multicenter study reports a Vision Transformer-based pathology framework whose risk scores, validated in 2,552 glioma cases, predict survival and ...
RNA Sequencing Reveals Inflammatory Pathways Behind Ventilator-Induced Diaphragm Damage in Rats
Transcriptome sequencing of ventilated rat diaphragms identifies MAPK, PI3K-Akt, and Calcium signaling as inflammation-linked pathways associated with muscle fiber atrophy ...
p53 Reverses Bcl-2’s Pro-Survival Grip by Restoring MAM Function in Skin Cancer
New research in Cell Division shows that Bcl-2 overexpression promotes survival of cutaneous squamous cell carcinoma cells by altering mitochondria-associated ...
Meta-analysis of tomato RNA-seq data pinpoints drought-responsive genes
A heterogeneity-aware meta-analysis of four public tomato RNA-seq datasets identified 5,681 drought-responsive candidate genes and profiled ten of them by ...
Benchmark Finds STAR-Fusion Most Reliable for Detecting Gene Fusions in RNA-seq Data
A new benchmark of eight fusion detection tools shows STAR-Fusion performs most consistently across targeted and simulated bulk RNA-seq data.
Chromatin Study Links Inflammation to Endothelial Remodeling in Capillary Malformations
An integrative ATAC-seq and RNA-seq study of induced endothelial cells from capillary malformation patients identifies inflammation-associated chromatin remodeling and distal ...
Oxidative shock rewires gene expression in white rot fungus on wood
A new study shows that hydrogen peroxide treatment triggers distinct gene expression responses in the wood-decay fungus Phlebia radiata depending ...
RNA-seq Falls Short for TCR Repertoire Recovery, Review Finds
A review of matched-sample benchmarking studies finds standard RNA-seq recovers only 3–5% of TCR clonotypes identified by dedicated TCR-seq.
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