Tag: Proteomics

A matched multi-omics study of 180 children in Niger identifies extracellular matrix proteins and sphingolipid disturbances as molecular signatures of ...

A new study identifies Tollip as a conserved negative regulator of ESCRT-III-mediated plasma membrane repair, showing that the protein balances ...

A Danish proteomics study found the calprotectin subunits S100A8 and S100A9 to be the most significantly elevated plasma proteins in ...

A UK Biobank study linked 681 blood proteins to cardiac MRI phenotypes and used genetic analysis to prioritize potentially causal ...

A cross-sectional ADNI study of 713 participants links neuropsychiatric symptoms to lower CSF amyloid-β42 and identifies heat shock protein pathways ...

A multicenter prospective cohort analysis finds that septic abdominal solid organ transplant recipients show better 30-day survival and a distinct ...

An integrative genomic and proteomic study identified seven new genetic loci and 23 genetically supported plasma proteins for age-related macular ...

An 11-protein signature from circulating extracellular vesicles, validated in an independent cohort, was associated with advanced fibrosis in MASH and ...

A new review surveys causal-inference methods applied to Alzheimer's molecular data, finding that many observational associations lack genetic support and ...

A time-resolved proteomic study in mice shows that loss of the desmosomal protein plakophilin-2 triggers right-ventricle-led molecular remodeling, with early ...

Structural, proteomic and modeling analyses of the emu eggshell show that the proteins DCA-1 and DCA-2 interact differently with calcium ...

A systematic review of 20 studies finds promising but preliminary biomarker evidence in urine and cerebrospinal fluid for detecting glioma.

BET inhibition suppresses STING expression at its promoter and enhancer regions, weakening the immune response triggered by PARP inhibitors.

Proteomic screening of nasal mucosal tissue from 30 patients identified RBM39 as upregulated in cases of re-obstruction after tear duct ...

CRISPR-engineered cervical cancer cells carrying the PIK3CA-E545K mutation show coordinated immune signaling and metabolic rewiring, driven by suppressed lipid biosynthesis ...

Multi-omics analysis of Haemaphysalis longicornis exposed to cinnamaldehyde identifies mineral absorption as a candidate pathway in the tick's stress response.

A mouse study found that adding carnosine during oocyte vitrification improved blastocyst formation rates and was associated with reduced oxidative ...

A new study reports that the cytokine IL-17A drives malignant T-cell proliferation in cutaneous T-cell lymphoma by increasing mitochondrial electron ...

A multi-omics study found that bacteriophage treatment reduced diarrhea in ETEC K88-infected weaned piglets while shifting gut bacteria, bile secretion, ...

A multi-omics study finds that liver fibrosis involves coordinated cell-type-specific metabolic remodeling, and that the phospholipid POPE reduces hepatic stellate ...