Tag: Osteogenesis

Clinicians identified osteogenesis imperfecta caused by a de novo COL1A1 variant in a neonate admitted for jaundice after multiple unexplained ...

A review examines how CRISPR-edited mesenchymal stromal cells could advance bone and cartilage repair while noting that clinical translation remains ...

Engineers have built a parallelized bioreactor that simultaneously delivers fluid shear stress and intermittent hydrostatic pressure to 3D bone tissue ...

In rat bone marrow stem cells, the TLR4 inhibitor TAK-242 suppressed LPS-induced inflammatory gene expression while leaving osteogenic differentiation largely ...

A new study finds that CD14-positive monocytes from rheumatoid arthritis and psoriatic arthritis patients show distinct inflammatory, metabolic, epigenetic and ...

A new cell study reports that liraglutide suppresses pressure-induced osteoclast differentiation and inflammation in macrophages while indirectly promoting osteoblast marker ...

Researchers report that alcohol depletes a protective microRNA in osteoclast-derived exosomes, and that restoring miR-378a-3p in rats reduces femoral head ...

A mouse study finds that the KCNE3-KCNQ1 potassium channel axis couples mitochondrial energy metabolism to vessel growth and bone formation, ...

Slicing king oyster mushroom stipes lengthwise rather than crosswise preserves a naturally aligned hyphal network that guides bone-forming cells, blocks ...

A sandwich-structured PVDF and silk fibroin hydrogel laced with MXene converts everyday mechanical stress into electrical stimulation, tipping the bone-fat ...

An architected polymer framework, bioactive glass and a soft hydrogel formed a composite that increased vascularized bone formation in rat ...

Sodium selenite reduced ferroptosis and improved bone formation through GPX4 in cell and ovariectomized mouse experiments, preclinical findings that do ...

A laboratory study found that removing heparan sulfate chains from perlecan in cell-derived extracellular matrix altered human stem-cell differentiation according ...

A 2026 review finds that CPNE7-derived peptides can promote selected tissue-repair processes in preclinical models when engineered into collagen and ...

Cell-culture and mouse experiments found that low-concentration simvastatin promoted osteogenic activity and endothelial network formation through a process associated with ...

Network analysis, mouse stem-cell assays and a murine periodontitis model indicate that aloe-emodin can suppress selected inflammatory signals while supporting ...

A mouse study finds that nutrient stress elevates ACSS1 in bone-forming cells, impairing mitochondrial function and bone formation through increased ...

A sustained-release nanofibrous membrane delivered wild-type stem-cell extracellular vesicles to improve bone formation in p75NTR-deficient mouse cells and cranial defects.

A bone-targeted exosome therapy carrying a miR-196b inhibitor and platinum nanoparticles preserved trabecular structure and reduced osteoclast activity in a ...

A titanium coating combining sodium alginate, collagen, and the plant-derived polyphenol troxerutin simultaneously boosts bone-forming and blood vessel-forming activity in ...