Tag: multiple myeloma

Researchers identified IGFBP5 as a negative regulator of adhesion-mediated bortezomib resistance in multiple myeloma that modulates FAK/Src signaling.

A retrospective study reveals that frontline daratumumab, lenalidomide, and dexamethasone provided durable disease control in transplant-ineligible multiple myeloma patients older ...

A retrospective service evaluation found that implementing an electronic medical record and tailored case report form substantially increased complete documentation ...

A 2026 narrative review synthesizes evidence that inflammatory blood ratios, endothelial scores, and CAR-T-specific tools can stratify outcomes in hematologic ...

An adjusted cross-trial analysis found teclistamab plus daratumumab was associated with significantly longer progression-free and overall survival and deeper responses ...

The 25th International Cancer Imaging Society Meeting proceedings describe MRI biomarkers, structured reporting systems, and quantitative imaging tools that predict ...

A retrospective single-laboratory study of 267 bone marrow samples found that CD20 expression on plasma cells was more often retained ...

A Chinese case report documents an exceptionally rare presentation of Waldenström macroglobulinemia, in which an osteolytic lumbar vertebral fracture was ...

A new review maps how 3D bone marrow models, from spheroids to bioprinted and organ-on-chip systems, are being used to ...

Bone marrow stromal cells drive interleukin-6-mediated metabolic reprogramming and bortezomib resistance in multiple myeloma, a new open-access study reports.

A bioinformatic and preliminary experimental study identifies PTGS1, CA1, and SYK as prognostic genes in multiple myeloma and explores, without ...

A new review synthesizes the clinical evidence, toxicity profiles and resistance mechanisms behind six FDA-approved antibody-drug conjugates for blood cancers.

A case report describes a 64-year-old woman with multiple myeloma and an SCN5A overlap channelopathy who underwent autologous stem cell ...

A new review in Blood Research details how rare morphological and immunophenotypic variants of plasma cell neoplasms mimic lymphomas, carcinomas, ...

A retrospective cohort study of 100 patients finds that moderately severe kidney impairment at multiple myeloma diagnosis independently predicts long-term ...

An automated deep learning pipeline measured skeletal muscle and fat with high agreement from same-day whole-body MRI and low-dose PET/CT ...

A prospective single-center observational study found that patient-reported physical and functional burden after CAR T-cell therapy peaked during hospitalization and ...

A new mass spectrometry assay identifies patient-specific M-protein peptides in plasma without sequencing, showing generally concordant longitudinal trends with conventional ...

A retrospective study of 128 multiple myeloma patients links distinct CRS symptom profiles to onset timing, severity and duration after ...

A new editorial argues that extracellular vesicles both drive tumor adaptation and drug resistance and offer promising platforms for antitumor ...