Tag: multiple myeloma

Nearly half of patients with multiple myeloma experience pathological fractures, according to a retrospective analysis of 692 cases treated at ...

An observational cohort study of newly diagnosed hematologic cancer patients found that higher daily step counts measured by Fitbit trackers ...

A retrospective Chinese cohort found similar 3-year survival with oral and intravenous melphalan conditioning, but different engraftment and toxicity patterns.

The BELI(E)VE protocol describes a German phase I/IIa trial of belantamab mafodotin plus venetoclax, with or without dexamethasone, in t(11;14)-positive ...

A review of 11 studies found hypertension associated with a 90% higher cardiovascular-event risk in multiple myeloma, while treatment exposure ...

A National Cancer Institute grant will fund planned OU trials testing whether opaganib can enhance CAR T-cell activity against ultra-high-risk ...

A new study identifies UBA1 as a primary candidate biomarker for multiple myeloma by integrating ubiquitination and liquid-liquid phase separation ...

A consumer-informed Australian pilot study found that an existing group mental health program significantly improved wellbeing and empowerment among people ...

Chimeric antigen receptor T cell therapy has redefined the treatment of multiple myeloma, offering deep and durable remissions to patients ...

A phase 2 trial found that ultra-low-dose radiation therapy delivered in one or two sessions relieved painful bone lesions in ...

A new computational study suggests that next-generation CRBN E3 ligase modulators, particularly CC-885, may hold the key to overcoming mutation-driven ...

A retrospective cohort study using the MIMIC-IV database found that elevated blood urea nitrogen within 24 hours of ICU admission ...

A new method-comparison study finds that a domestic Chinese latex-enhanced immunoturbidimetric serum free light chain assay shows precision and agreement ...

Researchers adapted a thermodynamics-based modeling language from ecology to reproduce the full life cycle of the adaptive immune response across ...

A phase 1 trial found that the investigational BCMA-targeted CAR-T therapy anito-cel produced responses in all 38 participants with relapsed ...

A prospective real-world cohort study finds that proteasome inhibitor-based therapy is not associated with measurable differences in quality of life, ...

The British Journal of Cancer has retracted a 2014 study linking chromatin structure and DNA repair to chemotherapy outcomes in ...

A Japanese case report describes how the myeloma drug pomalidomide rapidly relieved transfusion-dependent nosebleeds in a patient with hereditary hemorrhagic ...

New research reveals that resistant myeloma cells import putrescine through the transporter SLC45A4, activating HOXA1-driven NF-kappaB signaling with help from ...

A new review argues that stable isotope fractionation patterns, long used to reconstruct Earth's history, could become mechanistic biomarkers for ...