Tag: Mitochondrial dysfunction

A 69-microRNA signature measured in blood exosomes classified Parkinson's disease with an AUC of 0.952 across cohorts, while multi-omics analyses ...

A review proposes that ovarian aging is a progressive reorganization of immune, metabolic, and endocrine networks linking the ovary to ...

A 2026 mini review concludes that microglial metabolic states may connect brain pathology with adult neurogenic niche remodeling through phagocytosis, ...

A mouse study found that endothelial FoxO1 supports capillary remodeling, mitochondrial integrity and metabolic health in females while producing opposite ...

A 2026 review identifies multiple forms of programmed cell death as contributors to aortic dissection progression but finds limited clinical ...

AFAR awarded eight early career investigators nearly $1.3 million for one- to two-year projects on planned investigations into mechanisms of ...

An editorial reviewing 21 contributions argues that sepsis therapy is shifting from broad cytokine suppression toward phenotype- and timing-based treatments ...

A mouse study finds that nutrient stress elevates ACSS1 in bone-forming cells, impairing mitochondrial function and bone formation through increased ...

A yeast study found that combined plant fractions induced mitochondrial dysfunction and apoptosis-associated changes, with the strongest effects measured at ...

A plant-derived sterol called stigmasterol sabotages the metabolic machinery of glioblastoma cells by impairing mitochondrial function and increasing oxidative stress, ...

A new review in Molecular Biology Reports details how the dietary flavonoid apigenin combats oxidative stress, neuroinflammation, mitochondrial dysfunction, and ...

A new review argues that mitochondrial dysfunction is the central mechanism linking metabolic stress, inflammation, and nerve degeneration in diabetic ...

New research shows that arachidonic acid released during infection worsens podocyte kidney injury by disrupting PKM2-linked glycolytic metabolism and mitochondrial ...

A new review argues that recurrent mitochondrial metabolic stress, redox imbalance, and inflammatory signaling converge on the neurovascular unit to ...

A new study reveals that impaired proteasome function, driven by SUMOylation, may underlie the toxic accumulation of alpha-synuclein in Parkinson's ...

New research shows that the pro-fibrotic signal BMP4 drives mitochondrial dysfunction in kidney mesangial cells by suppressing Parkin, a key ...

A new comprehensive review maps the signaling pathways, biomarkers, and molecular signatures that determine whether heart muscle survives ischemic injury.

A new Frontiers in Cell Death Research Topic curated by women scientists collects five studies spanning necroptosis, death receptor glycans, ...

A new review argues that the longevity enzyme sirtuin 1 sits at the molecular crossroads between cellular senescence and heart ...

A new review proposes that electroacupuncture may ease long COVID by activating vagal cholinergic anti-inflammatory signaling and restoring mitochondrial metabolic ...