Tag: Metastasis

A new review in Annals of Gastroenterological Surgery proposes treating gastric cancer metastasis as distinct patterns, identifying route-specific biomarkers and ...

A retrospective study found that Ga-FAP-2286 PET/CT complements FDG in lung cancer, showing comparable primary detection but lower nodal and ...

A new study identifies lncRNAs LINC00504 and LINC00520 as key regulators of the balance between proliferative and invasive states in ...

A clinical case report documents an asymptomatic 73-year-old prostate cancer patient whose biochemical recurrence led to the rare detection of ...

Researchers have identified that exosome MS4A8 promotes prostate cancer bone metastasis and osteolytic destruction by activating NF-κB and AKT pathways ...

Pharmaceutical STING activation reduced primary tumor recurrence and extended survival in a mouse model of metastatic triple negative breast cancer.

A narrative review argues that PEAK1 acts as a context-dependent signaling scaffold in adhesion, growth factor pathways, metastasis and drug ...

Phosphorylation of KRAS at Ser181 promotes invasion and metastasis in colorectal cancer cells by regulating the secretion of lysosomal proteins, ...

A comprehensive review outlines how aging and tumor signaling remodel circulating platelets into hyperreactive, immunosuppressive cellular fragments that drive thromboinflammation ...

Researchers have discovered that basophils suppress early lung metastatic seeding by curbing regulatory T cells through histamine signaling and enzymatic ...

Genomic analysis of 71 tumors from 20 patients shows most secondary chest lesions in head and neck squamous cell carcinoma ...

An analysis of 172,512 German breast cancer cases shows that molecular subtypes are associated with both the timing and organ ...

A new review maps how genetic, epigenetic and immune changes drive colorectal cancer from its first transformation to metastasis and ...

An optimized on-tissue derivatization workflow using 4-APEBA and EDC enables confident MALDI-MSI mapping of carbonyl- and carboxyl-containing metabolites in mouse ...

A new review proposes that the constantly shifting shapes of proteins, not just genetic mutations, drive rapid and reversible drug ...

A new review in Breast Cancer Research outlines a framework for engineering CAR-NK cells to intercept circulating tumor cells, target ...

A new review proposes that mature tumor cells can dedifferentiate into cancer stem cells, acting as a non-genetic engine of ...

B7-H6 expression on tumor cells and tumor-infiltrating leukocytes is linked to metastasis, lymph node spread and reduced overall survival in ...

A new Cell Division study reports that the transcription factor PRRX2 activates the CNTN3 gene, promoting epithelial-to-mesenchymal transition, proliferation and ...

A new review describes how platelet–neutrophil crosstalk and NETosis create premetastatic niches and outlines nanotherapeutic strategies for early anti-metastatic intervention.