Mixed-effects radiomics model hits AUC 0.91 for lung cancer prediction across seven UK hospitals
A retrospective UK study of 1,026 patients found that a mixed-effects radiomics model achieved an AUC of 0.91 for predicting ...
Tag: lung cancer
Seven Minutes May Be Enough: Faster Chest PET/MRI Scans Match 20-Minute Image Quality
A retrospective reconstruction study of 101 chest PET/MRI scans found that a 7-minute PET acquisition matched a 20-minute reference for ...
Cubosome integrated with polymeric carbon nitride and cisplatin: in vivo biodistribution and in vitro photodynamic therapy studies
A new lipid cubosome carrying carbon nitride and cisplatin accumulated preferentially in mouse lungs and killed cancer cells under light ...
U-Net Variants Compared for Automated Lung Tumor Segmentation on CT Scans
A comparative study of nine U-Net-based deep learning configurations found U-Net with a VGG16 backbone achieved the best overall lung ...
Qualitative Study Builds a Preliminary Skill Model for Lung Cancer Caregivers
A grounded-theory study of 23 caregivers and oncology staff in Shenzhen identified six categories of care ability for lung cancer ...
Four Radiomic Texture Features Survive the Leap from Clinical CT to Micro-CT in Lung Cancer
A study of 60 NSCLC patients finds that only four texture-based radiomic features remain reproducible across clinical CT, ex vivo ...
EGF-depleting vaccine plus nivolumab shows survival signal in advanced NSCLC
A phase II trial reports 11.9-month median overall survival with CIMAvax-EGF plus nivolumab in previously treated advanced NSCLC, with the ...
Newly found enzyme pathway helps cancer cells churn out KRAS growth proteins
New research from MD Anderson shows the METTL13 enzyme helps cancer cells selectively produce growth-driving proteins such as KRAS, and ...
LDCT Spots Lung Cancer Recurrence Early, but Misses Brain and Bone
A retrospective cohort study of 150 postoperative lung cancer patients found that LDCT-detected recurrences clustered in the first year after ...
Blue laser light plus porphyrin drug pushes lung cancer cells into senescence
A 450-nanometer blue laser combined with the photosensitizer sinoporphyrin sodium suppressed lung cancer cells and xenograft tumors by triggering ROS-dependent ...
Experts Build Consensus Framework to Prevent Blood Clots in Lung Cancer Patients
A two-round Delphi study with 15 experts in Nanjing produced a 34-indicator framework for organizing hospital-based venous thromboembolism prevention in ...
Enzyme PLA2G4A fuels lung cancer growth through an HSF1 signaling axis
A new study reports that the enzyme PLA2G4A promotes non-small cell lung cancer proliferation, survival and metastasis through an SP1–IL-1β–MAPK–HSF1 ...
AI lung cancer screening shows promise but falls short of clinical autonomy
A systematic review and meta-analysis finds pooled sensitivity of 85.4 percent and specificity of 83.5 percent for deep learning-assisted low-dose ...
In vivo isotope tracing maps fat-making flux in KRAS lung tumors and host tissues
In vivo isotope tracing in KRAS-driven lung cancer mouse models shows that tumor fat synthesis draws mainly on lactate and ...
Chalcone compound UR-2 kills stem-like lung cancer cells by disrupting mitochondrial redox signaling
A hydroxylated chalcone derivative called UR-2 suppressed the growth of CD133-positive lung cancer organoids by lowering Thioredoxin-2 expression and triggering ...
Asbestos May Be Fueling China’s Rising Lung Cancer Rates, Review Finds
A new review argues that asbestos exposure, including ongoing chrysotile use and legacy materials, is systematically underestimated as a contributor ...
Cancer gap widens between people with and without type 2 diabetes
A nationwide Danish study presented at the EASD annual meeting found cancer incidence was 12% higher in men and 22% ...
Long Non-Coding RNA LINC01140 Shows Dual Roles Across Human Cancers, Review Finds
A new review in Cell Division finds that the long non-coding RNA LINC01140 acts as an oncogene in some cancers ...
Lung Cancer Surgery Succeeds After Near-Fatal Immunotherapy Heart Complication
A case report documents curative lung resection 144 days after a patient survived grade 4 immune checkpoint inhibitor-associated myocarditis during ...
Pleural Fluid LDH Levels Linked to Shorter Survival in Lung Cancer Patients
A retrospective study of 71 lung cancer patients found that higher pleural fluid lactate dehydrogenase was associated with shorter overall ...
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