Transcription Factor YY1 Drives Radiotherapy Resistance in Lung Adenocarcinoma Through PMVK
A study reveals that the transcription factor YY1 transcriptionally activates PMVK to suppress ferroptosis and promote radiotherapy resistance in lung ...
Tag: lung adenocarcinoma
Lung Cancer Study Links RNA Sponge to Chromosomal Instability
A 2025 in silico study in Cell Division identifies a ceRNA axis involving TMPO-AS1 and let-7b-5p that upregulates chromosomal passenger ...
Nested CT Habitat Score Distinguishes Lung Adenocarcinoma Grades in Multi-Center Study
A retrospective two-center study of 650 patients found a CT-derived nested habitats score discriminated IASLC Grade 1 from Grade 2 ...
PSMB7 Linked to Lung Adenocarcinoma Progression, Radiation Resistance, and Prognosis
Researchers evaluated PSMB7 across multiple datasets and cell lines, identifying it as an independent prognostic biomarker linked to immune microenvironment ...
Computational Analysis Uncovers Shared Genetic Landscape Linking Atherosclerosis and Lung Adenocarcinoma
A multi-cohort transcriptomic study identified shared genetic biomarkers and immune mechanisms connecting atherosclerosis and lung adenocarcinoma, providing new models for ...
Computational Analysis Links BUB1 and Noncoding RNA Network to Lung Adenocarcinoma Outcomes
A computational study evaluating multi-omics databases found that elevated BUB1 expression driven by a noncoding RNA regulatory network correlates with ...
ER stress stratification points to DKK1 as a driver of lung adenocarcinoma progression
A molecular stratification of endoplasmic reticulum stress in lung adenocarcinoma identifies DKK1 as a tumor-cell-biased prognostic regulator linked to ER-phagy-related ...
Tumor Cell State Linked to Low Angiogenesis Identified in Lung Adenocarcinoma
A SCGB3A2-high tumor cell state in lung adenocarcinoma shows low angiogenesis and is associated with extracellular PGK2 and angiostatin signals.
Review Proposes Age Decompression Framework for Cancer Risk in Lung Cohorts
A review synthesizing aging biology, geriatric oncology, and public lung adenocarcinoma cohort analyses proposes an age-decompression framework to reposition chronologic ...
Rare Fetal Lung Adenocarcinoma Traced Across Ten Tumor Cases
A retrospective analysis of ten fetal lung adenocarcinoma cases at a single Chinese hospital describes distinct low-grade and high-grade pathological, ...
Scientists reveal how a methyl tag on eEF1A speeds KRAS translation and fuels cancer drug resistance
St. Jude scientists showed that METTL13-driven methylation of the translation factor eEF1A selectively speeds decoding of codons enriched in oncogenes ...
Machine learning pinpoints a 40-lncRNA signature linked to lung adenocarcinoma survival
A machine learning analysis of 349 lung adenocarcinoma cases identified a 40-lncRNA signature that separated patients by overall survival and ...
Engineered NK Cells Target CD73 to Attack Hard-to-Treat Lung Adenocarcinoma
Preclinical research shows that natural killer cells engineered with a CD73-targeting receptor kill relapsed or refractory lung adenocarcinoma cells in ...
Nomogram Predicts Survival in Advanced EGFR-Mutant Lung Cancer on TKIs
A retrospective study of 250 patients developed a nomogram using age, EGFR genotype, CYFRA21-1 level, and TKI generation to predict ...
Long non-coding RNA TMPO-AS1 flags poor outcomes in lung adenocarcinoma
A multi-database bioinformatics study identifies the long non-coding RNA TMPO-AS1 as overexpressed in lung adenocarcinoma and linked to poor survival ...
Benign Tumor at a Lung Surgery Port Site Fooled Doctors Into Fearing Cancer Recurrence
A case report describes a rapidly enlarging chest wall mass at a thoracoscopic port site after early-stage lung cancer resection ...
Rare inherited MUC16 variants may underlie multiple lung cancers in one family
A case report describes rare germline MUC16 variants shared by four siblings with multiple primary lung adenocarcinomas, suggesting possible familial ...
Single-Cell Map Links Endothelial Cell Genes to Lung Cancer Survival
A six-gene endothelial cell signature built from single-cell RNA sequencing data predicts survival outcomes and reveals distinct tumor microenvironment communication ...
Methylated translation factor speeds decoding of rare codons to drive cancer growth
A methylation mark on translation factor eEF1A selectively speeds decoding of rare, wobble-weak codons, boosting KRAS production and driving resistance ...
RNA Methylation Enzyme NSUN2 Keeps Lung Tumors Cold and Blocks Immunotherapy
A new study reports that the RNA m5C methyltransferase NSUN2 suppresses CCL5-driven CD8+ T cell recruitment in lung adenocarcinoma through ...
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