Stem Cell Transplantation Eases Skin Inflammation in Systemic Sclerosis
A retrospective study of 29 severe systemic sclerosis patients found that autologous hematopoietic stem cell transplantation reduced epidermal thickness and ...
Tag: Immunohistochemistry
Melanin pigmented dentigerous cyst report of a case and review of relevant literature
A case report documents only the fifth known melanin-pigmented dentigerous cyst, a black, tar-like jaw lesion in a 27-year-old man ...
Rare Conjunctival Venous Malformation Removed After 20-Year Growth
A case report describes the diagnosis and successful surgical removal of an extremely rare cavernous venous malformation confined to the ...
Two SOD1 Aggregate Strains Differ in How Fast ALS-Like Disease Spreads to the CNS
In SOD1G85R mice, sciatic nerve inoculation with two distinct SOD1 aggregate strains transmitted templated aggregation to the CNS, with strain ...
Rare Ovarian Carcinoid Tumors Show Favorable Outlook in Seven-Case Analysis
A retrospective analysis of seven primary ovarian carcinoid cases found insular histology most common, frequent association with cystic teratoma, and ...
Cardiac sarcoma: new diagnostic framework proposed from two rare left atrial cases
Researchers in Singapore propose a multidisciplinary institutional protocol for diagnosing and treating rare primary cardiac sarcomas, illustrated by two left ...
Case Report: Metachronous multiple primary neoplasms in a carrier of germline MSH2 c.958dupA Lynch syndrome
A case report documents four metachronous neoplasms in one MSH2 mutation carrier over eight years, with only the endometrial cancer ...
Src kinase emerges as a molecular player in early tau pathology in Alzheimer’s disease
A new study links upregulated Src kinase and the transcription factor NEUROD2 to early tau pathology in Alzheimer's disease, supported ...
Erythrocytes as contrast agents: ultrasound technique resolves tumour microvessels in mice
A contrast-free ultrasound technique that tracks red blood cells has resolved tumour microvessels around 30 micrometres wide in mouse models ...
Peritoneal washings reveal cytologic clues to aggressive pilomatrix-like endometrioid carcinoma
A rare and aggressive variant of endometrial cancer has now been characterized under the microscope in a way that may ...
CT83 Protein Marks Triple-Negative Breast Cancer, but Its Aggressive Links Prove Indirect
A study of 222 breast cancer patients found CT83 expression in nearly half of tumors, with its ties to aggressive ...
Computational agent pinpoints ADAM17 as drug target in biliary tract cancer
An AI-driven target discovery framework ranked ADAM17 first for biliary tract cancer, and antibody-drug conjugates and CAR-T cells built against ...
Rare Bartholin Gland Cancer Case Highlights Diagnostic Delay and MYB Testing Limits
A case report in BMC Women's Health describes a 72-year-old woman whose decade-long vulvar pain preceded a diagnosis of extremely ...
How Forensic Scientists Tell Whether a Burn Happened Before or After Death
A new forensic review finds that classical histology and selected immunohistochemical markers remain the most reliable basis for distinguishing antemortem ...
Digital pathology quantifies immune cells in gastric biopsies with H. pylori infection
A cross-sectional digital pathology study of 154 gastric biopsies found that neutrophilic infiltration and lymphoid follicles were significantly associated with ...
Rare Chest-Only High-Grade Serous Carcinoma Reported in 60-Year-Old Woman
A case report describes a 60-year-old woman with Müllerian-type high-grade serous carcinoma confined to the pleura, with no primary tumor ...
Rare immune disease of the brain lining misdiagnosed as tumours in young Indian patients
A retrospective Indian cohort of nine biopsy-proven cases of CNS IgG4-related disease found the immune condition was almost never identified ...
Core Needle Biopsy Falls Short for HER2-Low Breast Cancer Classification, Study Finds
A retrospective study of 1,919 breast cancer patients in China found core needle biopsy reliably determines binary HER2 status but ...
Rare Ovarian Sertoli-Leydig Cell Tumor Mistaken for Leiomyosarcoma in 45-Year-Old Woman
A case report describes a rare poorly differentiated ovarian Sertoli-Leydig cell tumor with smooth muscle differentiation that was initially misdiagnosed ...
Rare Brain Tumor Puzzle: Fetal-Type Cancer in the Cerebellopontine Angle With No Lung Primary Found
A 61-year-old man's cerebellopontine angle tumor showed high-grade fetal adenocarcinoma features, but no lung primary could be found on initial ...
POPULAR NEWS
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Review Links Mitochondrial Dysfunction to Metabolic Liver Disease Progression
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Seawater Elements on Enamel May Aid Drowning Time Estimates