Tag: immune evasion

A review in Molecular Cancer details how dysregulated Hippo pathway signaling drives immune evasion across tumor, immune, and stromal cells ...

A scientific review details how CRISPR-Cas9 gene editing is advancing through preclinical models and early clinical trials to regenerate insulin-producing ...

A new study reveals that PIK3CA promotes liver tumor growth by helping tumors evade phagocyte-mediated immune responses, suggesting that PIK3CA ...

A new review maps how nerve, immune and tumor cell interactions drive pancreatic cancer progression, immune evasion, pain and treatment ...

A scientific review details shared metabolic reprogramming between atherosclerosis and cancer, establishing a theoretical foundation for potential common therapeutic strategies.

A comprehensive scientific review synthesizes viral host tropism into a five-stage molecular gatekeeping framework linking entry barriers, immune evasion, and ...

A transcriptomic profiling study identified ARSB as a candidate tumor suppressor that constrains colorectal cancer progression by coordinating ERK signaling ...

A new review consolidates evidence that the secreted protein DKK1 acts through multiple signaling routes and is associated with poor ...

A new review maps how African swine fever virus dismantles interferon signaling, inflammatory pathways, antigen presentation and lymphocyte function, explaining ...

A new review details how tumor cells import, export and steal mitochondria through nanotubes and vesicles to fuel growth, exhaust ...

A new cell-culture study shows that the Brucella effector protein BspJ enters the macrophage nucleus, binds the Zfp740 promoter through ...

A new review in Biological Procedures Online describes how activated neutrophils, through NETs and inflammatory mediators, may disrupt dormancy niches ...

A new study reports that NAT10-mediated mRNA acetylation and USP19-mediated deubiquitination jointly stabilize CDH3, promoting colorectal cancer progression and immune ...

A mouse study finds that neutrophils in breast cancer liver metastases suppress NK cell killing by contact-dependent downregulation of Eomes ...

A new review links EBV-driven lymphoproliferative disorders to disrupted DNA methylation and outlines emerging epigenetic treatment strategies.

Researchers found that the epigenetically silenced gene PRSS33 acts as a tumor suppressor and endogenous inducer of immunogenic cell death ...

Rabies virus matrix protein stabilizes RGS4 through incomplete autophagy, suppressing neuronal ferroptosis and supporting viral replication.

A new study reports that lactate in the pancreatic tumor microenvironment promotes metabolic reprogramming and PD-L1 upregulation through the TRMT6-SIRT5 ...

A new study reports that the recurrent CREBBP Y1503C mutation promotes diffuse large B-cell lymphoma growth and CD8+ T-cell dysfunction ...

A bibliometric analysis of 5,967 publications maps a decade of MDSC research, identifying leading countries, institutions, authors, and emerging research ...