Researchers engineered a chicory-derived germacrene A synthase to enhance the biosynthesis of beta-elemene in Saccharomyces cerevisiae.
Engineered laccase enzymes and functional carrier materials can efficiently degrade stubborn textile dyes, but most evidence still comes from laboratory-scale ...
Researchers in Japan engineered an ancestral nucleoside diphosphate kinase variant with a restricted amino acid repertoire and found that it ...
A new AI-guided design platform called HelixWings engineered two P450 enzymes to use the inexpensive biomimetic cofactor NMNH, boosting catalytic ...
A 16-billion-parameter AI model called Pinal designed proteins from natural-language descriptions that showed their intended functions in laboratory tests, including ...
Researchers engineered aldehyde dehydrogenases into oxidative ester synthases whose regioselectivity for primary or secondary alcohols is controlled by imidazole acting ...
A 2026 review synthesizes plant, enzyme-engineering and microbial approaches to phytosterol production, including a reported engineered-yeast campesterol titer of 5.88 ...
Researchers have computationally designed artificial cysteine proteases from scratch that cleave peptide bonds with rate enhancements of up to ten ...
The new generative AI system RFdiffusion3 designs proteins and nucleic acids atom by atom, producing functional enzymes and RNA molecules ...
Researchers at ITQB NOVA have characterised the first bacterial galactose oxidase and engineered it into a biocatalyst up to 1800 ...
Molecular dynamics simulations of pyrimidine-nucleoside phosphorylase from Bacillus subtilis show that the enzyme's conformational state controls ligand retention and compound-specific ...
Crystal structures of an engineered hyperthermophilic sugar dehydrogenase reveal how two mutations relieve a steric barrier and boost calcium uptake ...
In the realm of synthetic biology, the quest to engineer DNA polymerases capable of synthesizing novel or noncognate nucleic acids ...
In the evolving landscape of sustainable chemistry, the quest for efficient, cost-effective, and environmentally benign methods to synthesize chiral molecules ...
