Tag: DNA Methylation

A retrospective study of 20 pediatric CNS tumors found long-read nanopore sequencing matched methylation arrays for copy-number profiling and tumor ...

A new mini-review argues that long-read sequencing is exposing repetitive DNA, extrachromosomal DNA and complex structural variation that conventional methods ...

A new review describes how UV radiation, chemical exposure and hormonal changes can alter melanin production through epigenetic mechanisms such ...

A new review finds lean patients with fatty liver disease respond better to fecal microbiota transplantation than obese ones, but ...

A new review in Clinical Epigenetics outlines how cell-free DNA liquid biopsy and machine learning could be combined for cardiovascular ...

A pan-cancer analysis of 16 tumor types finds that elevated DNA methylation variability is consistently associated with genomic instability, aggressive ...

A new mini-review outlines how epigenetic silencing of NK-activating ligands helps urothelial carcinoma evade immune attack and how DNMT and ...

A UK Biobank study of 181,955 participants links better cardiovascular health and slower biological aging to lower chronic respiratory disease ...

A chromosome-wide analysis of 89 human brain methylomes finds that the combined methylation of female X chromosomes is globally lower ...

Using native long-read nanopore sequencing, researchers have simultaneously mapped 5mC and 5hmC across the whole genome of human neuronal nuclei, ...

DNA methylation at the LINC01354 and LINC01510 long non-coding RNA loci rises with tumor stage, grade and metastatic spread in ...

A study of healthy volunteers aged 1.5 to 71 found that urinary levels of active DNA demethylation products decline with ...

An epigenome-wide study of 1,527 Korean adults confirms core lipid–methylation loci and links ABCG1 methylation to the association between accelerated ...

A genome-wide study of human cells finds 9,006 differentially methylated CpG sites and 1,526 differentially methylated regions during osteoclast differentiation.

A new review in Frontiers in Endocrinology synthesizes molecular biomarkers, including DNA methylation and liquid biopsy indicators, that may help ...

A methylation comparison of human gingival fibroblasts, their derived iPSCs and an embryonic stem-cell reference found broad pluripotent-state convergence alongside ...

A urine-based DNA methylation marker, TAGMe, was associated with poorer outcomes in urothelial carcinoma and improved preoperative risk prediction in ...

A study of Indian cervical cancer patients links THOR hypermethylation to hTERT reactivation and reduced menin recruitment, independent of HPV ...

A new review maps four molecular routes by which CRISPR systems can detect cancer-linked DNA methylation in cell-free DNA, and ...

An observational analysis of 7,504 adults in two German cohorts linked adherence to 10 healthy dietary patterns with slower biological ...