Tag: DNA damage

Brachycerine, a UV-absorbing antioxidant alkaloid from the Brazilian tree Psychotria brachyceras, protected human skin samples from UV-A and UV-B damage ...

A new study in Cell Death Discovery shows that the PRMT6–SIRT5–HADHA pathway protects bone-forming osteoblasts from R-loop-induced DNA damage during ...

A new study shows that the Type III cif genes from the wAlbB Wolbachia strain induce cytoplasmic incompatibility in Drosophila ...

A new review synthesizes preclinical evidence that the CaMKIIδ kinase integrates calcium dysregulation, inflammation, autophagy failure, mitochondrial decline and DNA ...

A new in vitro study finds that mesoporous silica and graphene oxide both reduce cell viability and significantly increase mutations ...

Researchers built an in-cell ELISA that measures the DNA damage marker γH2AX in stable, non-proliferating human hepatocytes and detected dose-dependent ...

A screen of over 1400 FDA-approved compounds identified topoisomerase I inhibitors as the most effective partners for PARP inhibitors in ...

A 450-nanometer blue laser combined with the photosensitizer sinoporphyrin sodium suppressed lung cancer cells and xenograft tumors by triggering ROS-dependent ...

A preclinical study reports that 213Bi-labeled trastuzumab plus cetuximab killed human bladder cancer cells in vitro through irreparable DNA damage.

A ROS-responsive nanoparticle co-delivering a PARP inhibitor prodrug and a DOT1L inhibitor amplified DNA damage, activated cGAS-STING signaling and improved ...

A 12-week mouse study found that a soybean oil diet produced significantly higher blood DNA adduct levels and greater liver ...

A Johannesburg study tracked micronuclei in thyroid cancer patients for six months after radioactive iodine therapy and found chromosomal damage ...

A methanolic trunk bark extract of Balanites aegyptiaca reduced viability and triggered DNA damage in two breast cancer cell lines ...

Placentas affected by late-onset pre-eclampsia show hallmarks of accelerated ageing, with oxidative stress and reduced TERRA molecules identified as contributing ...

A literature review finds stronger experimental support for cellular senescence as a cause of age-related decline than for somatic DNA ...

A peer-reviewed study in the asexual bdelloid rotifer Adineta vaga shows how fragmented chromosomes can be retained across generations and ...

An experimental cell study finds that cohesin rapidly reorganizes stressed DNA replication sites and suppresses an error-prone restart pathway, helping ...

An observational analysis of 959 prostate tumours from 1,001 men found that eight cellular processes account for 85% of DNA ...

A cell-based study found that selected thiourea and (thio)semicarbazone derivatives reduced UVB-associated oxidative, inflammatory and DNA damage in human dermal ...

Hungarian researchers have built a human induced pluripotent stem cell platform that reproduces the sensitivity of healthy dividing tissues to ...