Hearing Loss Tied to Cognitive Decline in Older Adults, Scoping Review Finds
A scoping review of 74 studies finds predominantly adverse associations between age-related hearing loss and cognitive decline among community-dwelling older ...
Tag: Cognitive Decline
Tau, Not Just Amyloid, May Drive the Fast Cognitive Hits of Sleep Loss, Researchers Argue
A new opinion article in Frontiers in Neurology argues that tau-related mechanisms, which respond rapidly to sleep loss, deserve far ...
Review links aging brain biology with tumor progression
A peer-reviewed literature review proposes that age-related changes in the brain microenvironment may interact bidirectionally with tumors, influencing progression, treatment ...
New Alzheimer’s Microsimulation Model Translates Slowed Cognitive Decline into Years of Independence
Researchers built a microsimulation model from biomarker-confirmed Alzheimer's disease patients showing that a 30% slowing of cognitive decline extends time ...
Social activities linked to better cognition across 24 countries
An observational analysis of five surveys across 24 countries linked participation in three or more social activities with higher cognitive ...
PET Imaging Advances Track Cancer Therapy, Metastases and Dementia Signals
Six ahead-of-print studies in The Journal of Nuclear Medicine report PET tracking of radiolabeled trastuzumab deruxtecan in preclinical tumors, astatine-211 ...
Breast Cancer Drug Analysis Flags Dementia Signals for Anastrozole in Women Over 50
A large pharmacovigilance analysis of FDA adverse event reports found no overall dementia risk signal for endocrine and targeted breast ...
Donepezil-linked network gains fade as cognition and hippocampus decline
A 36-month retrospective study associated donepezil with early, short-lived brain-network gains but continued cognitive decline and left-hippocampal atrophy in Alzheimer’s-related ...
MRI-Estimated Brain Age Predicts Memory Decline in Healthy Older Adults
In a large Icelandic cohort, MRI-estimated brains that appeared older than participants’ chronological ages were associated with poorer baseline cognition ...
Immature brain support cells linked to poorer reasoning in older adults
A USC-led study of 29 adults with epilepsy found that more abnormal immature astroglia in the hippocampus were associated with ...
Immature Astroglia Track Fluid-Intelligence Decline in Epilepsy Patients
An observational study of people with mesial temporal lobe epilepsy found that more pathological immature astroglia in the hippocampus was ...
House Soiling in Old Dogs May Signal Failing Brains, Not Bladders
A longitudinal study of 84 aging dogs found that house soiling was linked to age, dilute urine, and impaired executive ...
Gene-Linked Parkinson’s Disease Moves Faster: Landmark Chinese Cohort Tracks Its Fingerprint
A three-year study of 301 Parkinson's disease patients in Northeast China finds that GBA1 gene variants, present in 8.31 percent ...
Caudate Scan Pattern Predicts Rapid Cognitive Decline in Early Parkinsonism
A five-year Italian study found that early dopamine loss in the caudate nucleus on DAT-SPECT marks a parkinsonian phenotype with ...
Going Online and Getting Out: How Blended Social Lives Slow Aging in China
A seven-year study of over 14,000 Chinese adults finds that combining online and offline social activity is associated with slower ...
UTHealth Houston Scientist Wins $12 Million to Probe Brain Energy and Aging
Rima Kaddurah-Daouk of UTHealth Houston has received a five-year, $12 million National Institute on Aging grant to study how mitochondrial ...
Gut/Brain Inflammation Link in HIV Wins $5.8M NIH Grant
OHSU researchers have received a $5.8 million NIH grant to investigate whether lasting gut immune damage drives the neuroinflammation behind ...
Who Gets Left Behind Online? New Study Maps the Resources Behind Older Adults’ Technology Use
A study of 8,664 older South Koreans finds that age, education, income, cognitive decline, and self-rated health together shape technology ...
Hearing Loss in Aging Weakens the Brain’s Wiring, Massive Scan Study Finds
A study of more than 2,400 older adults finds that age-related hearing loss is linked to weaker structural brain connections, ...
Aging Brains Respond Differently in Males and Females, Mouse Study Reveals
A new study in accelerated-aging mice shows that a neurogenesis-boosting compound rescues memory and hippocampal plasticity in males but not ...
