Tag: Chagas disease

A prospective study in Colombia found point-of-care rapid tests demonstrated high accuracy for screening Trypanosoma cruzi infection during pregnancy.

An integrative metabarcoding study found Trypanosoma cruzi infection alongside domestic animal and human blood meals in peridomestic Triatoma costalimai vectors ...

A review by the CRUZIDERM Consortium suggests that persistent dermal parasite reservoirs explain vector transmission and diagnostic challenges in chronic ...

Metabolomics analysis identified serum small molecule panels that predict progression from asymptomatic Chagas infection to cardiac disease.

Deleting the lipid droplet kinase gene in Trypanosoma cruzi reduced lipid droplet accumulation, increased resistance to hydrogen peroxide, and sharply ...

A cluster-randomized trial in the Argentine Chaco found that oral fluralaner treatment of dogs significantly reduced house infestation by 47% ...

Trypanosoma cruzi, the single-celled parasite behind Chagas disease, has long frustrated drug developers... One of the more striking aspects of ...

Deep inside the metabolic machinery of two of the world's most neglected killers, a quiet revolution in drug discovery is ...

Researchers at the University of Liège and Rockefeller University have captured near-atomic-resolution cryo-EM structures of the trans-spliceosome, the essential RNA-processing ...

A large-scale reanalysis of 86 RNA-seq libraries shows that the developmental gene expression programs of Trypanosoma cruzi are largely conserved ...

A study of 901 Triatoma infestans bugs in Argentina shows that rare melanic individuals occur only in rural areas, form ...

Chagas disease has long been recognized as a silent and insidious health threat across the Americas, often escaping detection until ...