Cancer Gene E2F1 Bypasses Standard Rules to Trigger Cell Division
A new study in The EMBO Journal reveals that the cancer-linked gene E2F1 can trigger cell division via a shortcut ...
Tag: Cell proliferation
Lung Cancer Study Links RNA Sponge to Chromosomal Instability
A 2025 in silico study in Cell Division identifies a ceRNA axis involving TMPO-AS1 and let-7b-5p that upregulates chromosomal passenger ...
Circular RNA Circ_0004846 Drives Colorectal Cancer Progression Through the miR-342-3p/CCND1 Axis
A new study identifies the circular RNA circ_0004846 as a driver of colorectal cancer progression through the miR-342-3p/CCND1 axis and ...
EZH2 and E2F1 Upregulation with NF2 Alterations Drives Aggressive Meningiomas
A study of meningioma tumor samples and cell lines links NF2 alterations with upregulated EZH2 and E2F1 pathways to aggressive ...
Blood enzyme marker shows promise for lung cancer risk assessment in pooled analysis
A pooled analysis of 32 observational studies found serum thymidine kinase 1 protein levels rise from tumor-free individuals to lung ...
PRRX2-CNTN3 axis drives EMT and metastasis in colorectal cancer
A new Cell Division study reports that the transcription factor PRRX2 activates the CNTN3 gene, promoting epithelial-to-mesenchymal transition, proliferation and ...
Ancient Lamprey Gene Offers Clues to Evolution of AFF Transcription Factors
Researchers identified an AFF3 homolog in lamprey and found its conserved domains promote cell proliferation in HEK293T cells.
TTC39B emerges as a pan-cancer prognostic marker suppressing renal cancer cell growth
A pan-cancer analysis links TTC39B expression to prognosis and tumor immunity across 33 cancer types, with experiments showing the gene ...
Ellagic Acid Curbs Pancreatic Cancer Development in Hamsters by Targeting IL-6/STAT3 Signaling
A hamster study published in Genes and Environment found that dietary ellagic acid was associated with significantly reduced pancreatic carcinogenesis ...
Circular RNA CircMAP2K4 Drives Osteosarcoma Growth via the miR-515-5p/G3BP2 Axis
Researchers report that the circular RNA circMAP2K4 promotes osteosarcoma progression by sponging miR-515-5p and derepressing G3BP2, and that it is ...
Low CEBPD Expression Tied to Poor Breast Cancer Survival, Study Finds
Researchers report that the adipogenesis-related gene CEBPD is downregulated in breast tumors, serves as an independent prognostic indicator of survival, ...
TRIM29 drives liver cancer growth by tagging DAPK3 for destruction
TRIM29 promotes hepatocellular carcinoma growth by tagging the DAPK3 protein for proteasomal degradation, according to a new Cell Death Discovery ...
Switchgrass microbe’s extracts show selective growth-stopping activity against tumor cells
Crude extracts of the switchgrass-associated bacterium Bacillus proteolyticus OSUB18 stopped the growth of diverse solid tumor cell lines in laboratory ...
PCGF1 Drives Glioma Cell Growth by Raising Levels of CCDC34
A study combining database analyses, glioma tissue samples, and cell-line experiments reports that PCGF1 upregulates CCDC34, which is associated with ...
Biomimetic membrane recreates native-like conditions for intestinal organoid cells
A soft membrane combining an electrospun nanofibrous scaffold with porcine colon extracellular matrix produced more native-like growth, marker and morphology ...
Meta-analysis links serum TK1 to prostate cancer and tumor grade
A systematic review and meta-analysis of eight studies found elevated serum TK1 in prostate cancer and an association with higher ...
HLTF Linked to Prostate Cancer Cell Growth in Laboratory Study
A computational and laboratory study found that reducing HLTF diminished prostate cancer cell proliferation and suggested regulation of ZBP1-PANoptosome assembly ...
Five Aptamers Show Activity Against Triple-Negative Breast Cancer Cells
A five-aptamer panel reduced tumor-cell viability, proliferation, migration and colony formation in several triple-negative breast cancer cell lines, with variable ...
Coagulation-associated genes stratify acute myeloid leukemia and spotlight SPINT2
An integrated transcriptomic and laboratory study linked coagulation-associated gene activity to survival and immune states in acute myeloid leukemia, while ...
GFPT1 silencing curbs aggressive esophageal cancer cell behavior through ER stress
Cell experiments found that silencing GFPT1 reduced proliferation, migration and invasion in esophageal cancer cells, with a rescue experiment supporting ...
