Tag: biomarkers

The MEMTAB 2025 conference in Birmingham showcased new tools and studies scrutinising the evidence behind diagnostic tests, biomarkers and prediction ...

A new Frontiers in Neurology editorial argues that symptom resolution may mask persistent biological changes after repeated concussions.

A Phase II trial in Japan identified TCR signaling mutations and clonal hematopoiesis burden as biomarkers predicting dasatinib response in ...

A new review links EBV-driven lymphoproliferative disorders to disrupted DNA methylation and outlines emerging epigenetic treatment strategies.

A new Cell Division study reports that cadherin genes CDH1, CDH2, and CDH3 are upregulated in nasopharyngeal carcinoma cell lines ...

An 11-protein signature from circulating extracellular vesicles, validated in an independent cohort, was associated with advanced fibrosis in MASH and ...

A cross-sectional study of 56 type 2 diabetes patients and 57 matched controls found higher ESM-1 levels and ASCVD risk ...

In a nine-year cohort of 4,935 Chinese adults, high eGDR combined with high NCCR was associated with a 37% lower ...

A new review argues that stroke is the endpoint of progressive vascular failure and that translational models can uncover biomarkers ...

In a 69-patient observational cohort study, the neutrophil–lymphocyte ratio showed a weak positive correlation with AIDP severity, while albumin showed ...

A study of 60 NSCLC patients finds that only four texture-based radiomic features remain reproducible across clinical CT, ex vivo ...

A mini review finds i-FABP and gluten immunogenic peptides the most promising emerging biomarkers for detecting intestinal damage and monitoring ...

A new review maps five variables that determine whether necroptosis primes antitumor immunity or fuels tumor growth, positioning radiotherapy as ...

An integrative analysis of human NOA transcriptomic data and a Utf1 conditional knockout mouse model identifies ACTRT2 and AKAP4 as ...

A systematic review proposes a clinically actionable biomarker stratification for immunotherapy in microsatellite-stable colorectal cancer, where response rates to checkpoint ...

An exploratory case-control study identified 24 plasma microRNAs with corrected-significant differences in treatment-naïve primary progressive multiple sclerosis patients.

A narrative review proposes that APOE ε4 amplifies diabetes-related cognitive decline across metabolic, vascular, and neurodegenerative layers, while α-Klotho may ...

A retrospective bicentric study of 158 metastatic melanoma patients found that CT radiomics offered no conclusive improvement over simple tumor ...

A new review synthesizes evidence that metabolic stress may shape DNA methylation through methyl-donor availability, impaired demethylation, and chromatin changes ...

Clustering seven biomarkers in 175,642 Chinese adults revealed sex-specific metabolic profiles linked to type 2 diabetes, kidney disease and cardiovascular ...