Tag: biocatalysis

Engineered halohydrin dehalogenase IcHheG achieves high enantioselectivity in the biocatalytic synthesis of (R)-5-phenoxymethyl-2-oxazolidinone.

Springer has launched Catal, a new open-access journal dedicated to catalysis research, aiming to bridge fundamental and applied sciences and ...

Researchers engineered the filamentous fungus Ashbya gossypii with plant terpene synthases and an orthogonal biosynthetic pathway, achieving sabinene titers of ...

Researchers have identified and biochemically characterized two key initiating enzymes from a novel ulvan utilization locus in the marine bacterium ...

Researchers engineered an amine dehydrogenase to resolve a racemic bicyclic ketone precursor of the analgesic drug mirogabalin through selective amination ...

Researchers using an automated computational protein engineering pipeline have identified an active-site mutation that increases PET plastic film degradation up ...

Researchers engineered a chicory-derived germacrene A synthase to enhance the biosynthesis of beta-elemene in Saccharomyces cerevisiae.

A T271D mutant of L-Pantolactone dehydrogenase shows an 8.2-fold increase in whole-cell catalytic activity for D-pantolactone production.

Researchers engineered an Escherichia coli strain using sequential thermal and chemical regulation to convert 5-hydroxymethylfurfural into 2,5-furandicarboxylic acid with complete ...

Researchers established Rhizopus stolonifer as a biocatalytic platform that yields cyclic dipeptides and selectively biotransforms the antimalarial drugs artemisinin and ...

A repurposed imine reductase uses photoexcited NADP+ to generate P-centred radicals and forge chiral carbon–phosphorus bonds with divergent stereocontrol.

Engineered type III binuclear copper enzymes from Bacillus megaterium catalyze unnatural enantioselective radical halogenation and pseudohalogenation reactions.

Machine learning-guided engineering of yeast alcohol dehydrogenase produced variants with more than doubled activity toward trans-2-nonenal, and one variant also ...

A new open-access protocol uses continuous dynamic light scattering to track protein self-assembly minute by minute, with the full workflow ...

Chemists have created graphene-enzyme hybrids in which immobilized lipases induce the formation of palladium and copper nanoparticles that catalyze carbon-carbon ...

Researchers immobilized the alkane-degrading enzyme LadA on a polymeric support, boosting its thermal and pH stability and enabling reuse across ...

A Trametes versicolor laccase co-oxidized quercetin and caffeic acid into five derivatives with dramatically improved water solubility and UV stability, ...

Combinatorial biosynthesis in Magnaporthe grisea shows that cytochalasan P450 enzymes tolerate macrocycle size differences but are restricted by the stereochemistry ...

Researchers engineered a dual-layer alginate composite around magnetic nanoparticles and enzymes, preserving full activity below 80 °C and retaining over ...

A synthetic eight-residue peptide modeled on the cobalt nitrile hydratase metal-binding motif binds Co(II) in two distinct coordination states and ...