Coagulation-associated genes stratify acute myeloid leukemia and spotlight SPINT2
An integrated transcriptomic and laboratory study linked coagulation-associated gene activity to survival and immune states in acute myeloid leukemia, while ...
Tag: Apoptosis
Chilli extract shows preclinical activity against lung adenocarcinoma in rats
A chemically complex chilli-pepper extract reduced proliferation, inflammation and oxidative-stress markers in a DEN-induced rat model of lung adenocarcinoma, with ...
GFPT1 silencing curbs aggressive esophageal cancer cell behavior through ER stress
Cell experiments found that silencing GFPT1 reduced proliferation, migration and invasion in esophageal cancer cells, with a rescue experiment supporting ...
Radiation suppresses PiC, triggering mitochondrial dysfunction and glioma cell death
A mechanistic study in glioma cells and mouse tumor models links radiation-induced PiC suppression to mitochondrial dysfunction, sustained pore opening, ...
Machine learning and cell study link shikonin to Parkin-dependent activity in hypoxic triple-negative breast cancer
A machine-learning and cell-culture study found that shikonin induced necroptosis and apoptosis in hypoxic MDA-MB-231 breast cancer cells through a ...
Research report: HIV-1 Vpr: a multifunctional accessory protein with potential contributions to AIDS pathogenesis and persistence
A 2026 review concludes that HIV-1 accessory protein Vpr coordinates cell-cycle arrest, mitochondrial death, immune signaling and viral replication, but ...
Systematic review of 14 in vitro studies links natural products to apoptosis in salivary gland mucoepidermoid carcinoma
A systematic review of 14 in vitro studies found that natural products showed antiproliferative and proapoptotic activity in human mucoepidermoid ...
PD-L1-targeted nanosystem shows antitumor activity in triple-negative breast cancer cell and mouse models
A cell and mouse study found that a PD-L1-targeted silver, doxorubicin and manganese dioxide nanosystem increased particle uptake and produced ...
Synergistic restoration of NK cell cytotoxicity against solid tumors via sLTA-mediated dual-action modulation
An abstract summarizes in vitro evidence that sLTA enhanced NK-cell activity and sensitized HT-29 colon cancer cells to apoptosis in ...
Sevoflurane reduced myocardial injury in rat and cell ischemia-reperfusion models through a circ_SMG6-related pathway
A rat and cell study found that sevoflurane reduced measured myocardial and cardiomyocyte injury alongside changes in circ_SMG6 and TLR4/mTOR ...
Ivermectin blunts cisplatin effects in oral cancer cells
A laboratory study found that ivermectin weakened cisplatin-associated cytotoxicity, apoptosis and S-phase arrest in HN9 oral cancer cells.
MG53 degrades AMPKα and suppresses bladder cancer in preclinical models
Preclinical tissue, cell, and xenograft experiments found that MG53 promoted AMPKα degradation, reduced glycolytic metabolism and tumor growth, and increased ...
Mechanisms by which programmed cell death mediates immune evasion and antitumour immunity in oropharyngeal cancer
A review finds that programmed cell death can promote immune evasion or antitumour immunity in oropharyngeal cancer depending on pathway ...
Combined plant fractions induce mitochondrial dysfunction and apoptosis in yeast
A yeast study found that combined plant fractions induced mitochondrial dysfunction and apoptosis-associated changes, with the strongest effects measured at ...
Plant Compound Cardamonin Shields Neurons by Calming Overactive Brain Immune Cells
A new study shows the natural chalcone cardamonin calms LPS-activated microglia by suppressing the EGFR/PI3K/AKT1/ERK/NF-kappaB signaling axis, indirectly protecting SH-SY5Y ...
New Study Identifies UBA1 as a Key Biomarker in Multiple Myeloma
A new study identifies UBA1 as a primary candidate biomarker for multiple myeloma by integrating ubiquitination and liquid-liquid phase separation ...
How Infection Signals Push Kidney Filter Cells Into Leaks, Damage, and Cell Death
New research shows that sustained activation of the innate immune receptor TLR4 in podocytes triggers a reversible leak in the ...
Vaccine-Strain Measles and Mumps Viruses Team Up to Kill Colorectal Cancer Cells
A new experimental study shows that a combination of vaccine-strain measles and mumps viruses synergistically kills HT-29 colorectal cancer cells ...
Mitochondrial Complex I Emerges as a Resistance-Proof Weak Point in Parasite-Infected Cells
New research shows that inhibiting mitochondrial complex I kills Theileria annulata-infected cells, including drug-resistant ones, and reveals a conserved mitochondrial ...
Two BCL-2 Gene Variants Linked to Protein Levels and Aggressive Bladder Cancer
Brazilian researchers have found that a BCL-2 promoter variant influences protein expression in bladder tumors while a specific haplotype triples ...
POPULAR NEWS
-
Every Hour of Delay After an Open-Globe Injury Raises Endophthalmitis Risk, Study Finds
-
Cellular Study Links Hepatitis B Mutation to Altered Liver Cell Mechanics
-
Standardized Test Assesses Nutrition Knowledge Among Rural Women in Uttar Pradesh
-
Meta-Analysis Assesses Targeted Therapies for MET-Altered Non-Small Cell Lung Cancer