Tag: angiogenesis

A new study uses single-cell RNA sequencing to explore the tumor microenvironment in NF2-related and sporadic vestibular schwannomas, identifying endothelial ...

Researchers found that circular RNA circUBR5 promotes ovarian cancer progression and angiogenesis in cell and animal models through a hypoxia-driven ...

Researchers identified the palmitoyltransferase ZDHHC8 as an oncogenic driver in clear cell renal cell carcinoma that regulates the FOXA2–ceruloplasmin axis ...

A new review argues that 3D-printed bone scaffolds still lack the functional, perfusable vascular networks needed for clinical translation.

Researchers demonstrated that the natural pentacyclic triterpene uvaol inhibits blood vessel formation by targeting key kinase enzymes in computational, enzymatic, ...

Researchers developed a contrast-enhanced MRI radiogenomic surrogate reflecting a composite hypoxia, angiogenesis, and epithelial–mesenchymal transition transcriptional state that associates with ...

A new study reports that restoring the integrin subunit ITGA5 accelerated wound closure in diabetic mice by protecting endothelial mitochondria ...

Researchers have demonstrated that the phosphatase inhibitor sodium tungstate accelerates host vascularization and doubles tissue survival in transplanted human beta-like ...

Researchers have discovered that the mitochondrial transporter SLC25A13 directs glutamine metabolism toward cholesterol and nucleotide synthesis to sustain endothelial cell ...

A narrative review argues that PEAK1 acts as a context-dependent signaling scaffold in adhesion, growth factor pathways, metastasis and drug ...

Circulating levels of the angiogenesis inhibitor endostatin are selectively reduced in chronic hepatitis C patients without steatosis and normalize following ...

A comprehensive review details the molecular and cellular mechanisms governing endometriotic lesion establishment, persistence, and progression, highlighting emerging mechanism-based therapeutic ...

An educational review argues that bronchopulmonary dysplasia arises from microRNA dysregulation spanning placental development through neonatal lung injury.

A SCGB3A2-high tumor cell state in lung adenocarcinoma shows low angiogenesis and is associated with extracellular PGK2 and angiostatin signals.

A new review describes theoretical simulation methods for studying blood flow, oxygen exchange, flow regulation and structural remodeling in microvascular ...

A new zebrafish study shows the transplant drug mycophenolate mofetil disrupts embryonic blood vessel development by inhibiting IMPDH and MAPK ...

A mouse study reports that CD34+ telocytes promote angiogenesis and wound healing by signaling to endothelial cells through Sema3c and ...

A narrative review consolidates preclinical evidence that the carotenoid astaxanthin inhibits breast cancer cell proliferation, metastasis and angiogenesis, while stressing ...

A cell-culture study found that cannabinoid receptor 1, highly expressed in rheumatoid arthritis synovial tissue, restrains fibroblast-like synoviocyte proliferation, invasion, ...

In a rat model of enterocutaneous fistula, gelatin sponges loaded with hypoxia-preconditioned exosomes reduced inflammation, shifted macrophages toward a reparative ...