Cancer
Editors Retract Breast Cancer Study After Overlapping Migration and Invasion Images Surface
The editors of Cancer Cell International have retracted a 2015 breast cancer study on cyclin D3 after discovering overlapping migration...
Mystery Cell Found: Why Enlarged Prostate Strikes Only One Zone of the Gland
Johns Hopkins researchers have identified a WIF1-expressing basal epithelial cell type concentrated in the prostate's transition zone and expanded in...
Exercise Stress Test Emerges as Gold Standard for Childhood Cancer Survivors’ Heart and Lung Fitness
A new review argues that cardiopulmonary exercise testing should become a standard tool for detecting and treating the hidden cardiorespiratory...
Mitochondrial Quality Genes Yield Seven-Gene Prognostic Signature for Breast Cancer
Researchers report that mitochondrial quality regulation gene activity defines two prognostically distinct breast cancer subtypes and supports a seven-gene survival...
NCCN Summit Puts Cancer Prevention and Screening at the Heart of Health Policy
The National Comprehensive Cancer Network's two-day Oncology Policy Summit in Washington, D.C. united leaders from the NCI, CDC, and advocacy...
The Hidden Cost of Cancer Care: When Treatment Steals Patients’ Time
A new scoping review of 30 studies synthesizes the emerging evidence on time toxicity in cancer care, showing how treatment...
Real-World Data Show Trastuzumab Deruxtecan Extends Survival in HER2-Low Metastatic Breast Cancer
A real-world cohort of 126 Chinese patients shows trastuzumab deruxtecan delivers a median 9.1 months of progression-free survival in HER2-low...
NIH Pioneer Award Backs Scientist Building Cancer Therapies That Evolve Alongside Tumors
NIH has awarded its Director's Pioneer Award to Sylvester Comprehensive Cancer Center virologist Leor Weinberger for developing an evolving oncolytic...
One in Five Lymphoma Patients on R-CHOP Suffers Febrile Neutropenia, Real-World Analysis Finds
A new systematic review finds that about one in five adults with diffuse large B-cell lymphoma develops febrile neutropenia during...
Hidden Fibroblast Subtype Drives Lung Cancer Growth and Weakens Immunotherapy
A multimodal single-cell and spatial study has uncovered a collagen-producing fibroblast subtype enriched in EGFR-mutant non-small cell lung cancer that...
Metastatic Cancer Patients Living Years Longer: Dutch Registry Reveals a Fourfold Surge
A Dutch registry study finds the number of patients living long-term with de novo metastatic incurable cancer more than quadrupled...
Tracer Debate: Fluorinated MIBG Alternative Sparks Scientific Exchange in Neuroblastoma Imaging
A scientific exchange in Pediatric Radiology over the merits of fluorinated MIBG PET imaging highlights the evidence still needed before...
Pediatric Neurosurgeon Michael Taylor Receives Inaugural Texans Conquer Cancer Award for Brain Tumor Research
Texas Children's pediatric neurosurgeon Dr. Michael Taylor has been named one of the first four recipients of CPRIT's Texans Conquer...
Barcode-Based Mutagenesis Assay Reveals Strand-Bias Rules Behind Oxidative DNA Damage
A barcoded shuttle-vector sequencing assay shows that chronic low-dose gamma irradiation amplifies pre-existing mutation hotspots driven by a single 8-oxo-G...
Why the Mouth Matters: Dentists Join the CAR-T Therapy Team
Hematologists argue that preventive dental care and oral health assessment should become a standard part of the CAR-T cell therapy...
Antibody–Drug Conjugates Emerge as Immune Modulators, Not Just Targeted Chemotherapy
A new review argues that antibody–drug conjugates act as immune modulators through immunogenic cell death, Fc-mediated effector functions and tumour...
Paolo Tomà , Pioneer of Paediatric Radiology, Dies at the Height of His Legacy
Professor Paolo Tomà , a pioneering Italian paediatric radiologist who led imaging departments in Genoa and Rome and shaped radiation protection...
Inflammation-Driven Spatial Niche Sets the Stage for Early Gastric Cancer
A spatial multi-omics study in Chinese Medical Journal shows that early gastric cancer arises within an inflammation-associated spatial niche governed...
The Hidden Architects of Colorectal Cancer: How Fibroblasts Drive Treatment Failure
A new review in Cancer Cell International details how cancer-associated fibroblasts remodel the colorectal tumor microenvironment and drive resistance to...
Rare Spinal Cord Tumors Get a Molecular Makeover in New Pediatric Review
A new comprehensive review synthesizes the molecular classification, surgical strategy, and pediatric-specific evidence gaps in spinal ependymoma management.
