Biology
Bacterial and fungal diversity varies across Anopheles larval habitats by productivity
In the shallow pools, puddles and water-filled depressions where malaria mosquitoes begin life, the most important clue may be invisible....
Norovirus Diagnostics Transform Through Innovation, Contextual Needs, and Collaborative Efforts
Norovirus Testing Enters a New Era as Rapid Molecular Tools Challenge the PCR Gold Standard Norovirus diagnostics are undergoing a...
Gut bacterial enzyme unlocks polysaccharides’ power to boost cancer immunotherapy
A molecule released by gut bacteria could help determine whether cancer patients respond to one of modern oncology’s most powerful...
Light Acclimation Across Photobioreactor Depth Boosts Biomass Production in Picochlorum renovo
A microscopic green alga has demonstrated a powerful strategy for turning uneven light into remarkably consistent growth, a finding that...
Multi-omics study reveals HMOX2 epigenetic control of beef color
A gene linked to the breakdown of blood pigments may help explain why beef from cattle kept in restrictive housing...
Mitochondrial DNA Mutation Causes Early Intestinal Epithelial Dysfunction During Acute Colitis
A mutation in mitochondrial DNA can disrupt the intestine’s frontline defenses long before the effects of aging become visible, according...
Professional Academies Urged to Lead Science Forward
Scientific academies are being urged to turn prestige into public service, as a new perspective argues that election to an...
Gene-level RNA sequencing masks widespread transcript-level remodeling during adaptation to hypoxia
Oxygen deprivation may be rewriting the molecular instructions inside cells far more extensively than conventional RNA sequencing analyses reveal, according...
Gambusia Generalists and Specialists Show Cognitive Flexibility Across Diverse Habitats
A Tiny Texas Fish Reveals How Generalists Outthink Specialists in Unpredictable Habitats When the environment changes without warning, survival may...
Versatile cGAMP Reporter Reveals How DNA Damage and Chromosome Instability Activate cGAS
A new study has introduced a molecular reporter designed to show, in real time, how human cells detect DNA damage...
Common European birds and butterflies predicted to decline despite conservation policies
Europe’s most familiar birds and butterflies may continue to disappear from the landscape even if governments achieve major conservation goals,...
Predicting Effects of Human Missense Variants Using Functional Evidence
A new artificial-intelligence-based approach could make one of genetics’ most difficult problems substantially easier: determining which single-letter changes in DNA...
Neutrophil-Integrated Syncytial CAR Macrophages Show Promise for Cancer Immunotherapy
Cancer immunotherapy has gained a hybrid new contender: a living cell engineered by fusing two immune-system specialists into one tumor-hunting...
Scientists Image Neuronal Voltage Across Entire Larval Zebrafish Brains
Seeing a brain think in real time has long been one of neuroscience’s most ambitious goals. A new study reported...
MINFLUX Reveals How Dynein Takes Productive Steps
A molecular motor that hauls cargo through the interior of cells appears to advance in a surprisingly intricate rhythm: each...
Isolated SACSIN HEPN Domain Exhibits RNA-Binding Activity
A previously unrecognized ability of a protein fragment linked to a rare inherited neurological disorder could reshape scientists’ understanding of...
TUDCA restores maturation of aged eggs in vitro by reducing ER stress
A Bile Acid Derivative Could Help Restore the Maturation of Aging Eggs A compound best known for protecting cells from...
UIDDA Unifies Model and Classifier Inputs to Predict Drug-Disease Associations
A new benchmarking framework is challenging a hidden weakness in artificial-intelligence research aimed at discovering which drugs might treat which...
Geochemical Constraints Shaping Sediment Microbiomes in Gypsum Caves Revealed
Beneath the sun-baked landscape of southeastern Spain, an underground microbial world is being shaped by chemistry that changes from one...
JAK2V617F Gold Nanoparticles Suppress IRF7 and TLR9 Activation
Gold Nanoparticles Rewire Inflammatory Signals in Cells Carrying a Cancer-Linked JAK2 Mutation Tiny gold particles carrying genetic targeting molecules have...