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Home NEWS Science News Technology

Amyloid-Inspired Coatings Keep Fruit Fresh Longer

Bioengineer by Bioengineer
May 31, 2025
in Technology
Reading Time: 5 mins read
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In a groundbreaking development that could revolutionize food preservation and reduce global food waste, scientists have unveiled a novel coating technology that remarkably extends the freshness of fruits through the application of amyloid-like protein coatings. This innovation, detailed in a recent publication in Nature Communications, carries profound implications for the agricultural supply chain, postharvest handling, and consumer consumption patterns by effectively slowing down the natural degradation processes of perishable produce.

Fruits, inherently delicate and prone to rapid spoilage due to moisture loss, microbial growth, and enzymatic degradation, have long challenged researchers seeking effective preservation methods. Traditional practices—ranging from refrigeration to chemical treatments—often fall short of significantly prolonging shelf life without compromising safety or environmental sustainability. The newly discovered approach leverages the unique structural properties of amyloid-like protein assemblies to form ultra-thin, transparent barriers around fruit surfaces that act as both protective shields and functional biochemicals to mitigate deterioration.

At the core of this technology is the generation of proteinaceous coatings that mimic the self-assembling amyloid fibrils commonly associated with disease-related protein aggregates, yet here harnessed in a beneficial context. These fibrillar protein matrices possess remarkable mechanical strength, resistance to enzymatic degradation, and exceptional adhesion to the complex surfaces of fruit skin. Through controlled polymerization and surface-binding techniques, researchers engineered coatings that are robust yet flexible enough to accommodate the natural respiration and physiological changes of fruits postharvest.

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One of the central scientific breakthroughs of this study lies in the fine-tuning of the protein assembly process, which creates nanoscale networks that can simultaneously allow gas exchange while limiting water vapor loss. Fruits naturally continue to respire after being harvested by consuming oxygen and releasing carbon dioxide and water vapor. The coating’s nanoporosity ensures oxygen permeation necessary to maintain cellular function yet retards water evaporation, which is a main driver of weight loss and texture degradation. This delicate balance is achieved by manipulating the fibril density and cross-linking within the coating matrix, an advancement representing a significant leap over previous film and wax coatings that largely functioned as impermeable barriers.

Furthermore, the coatings exhibit intrinsic antimicrobial properties imparted by functional groups present on the protein fibrils, which can be further modified chemically to enhance defense against fungal and bacterial invasion. Such infections are a significant cause of fruit spoilage and economic loss. By limiting pathogen colonization on the fruit surface, the coating reduces decay without resorting to synthetic fungicides or preservatives, thus catering to the rising consumer demand for natural, residue-free produce.

Experimental trials showcased the coating’s efficacy on a variety of fruits including apples, strawberries, and cherries—each with distinct respiration rates and skin textures. The treated fruits demonstrated a dramatic extension of shelf life, maintaining firmness, color, and nutrient content for periods up to 50% longer than untreated controls. Crucially, taste tests confirmed that the edible coatings imparted no perceptible changes to flavor profiles, an essential factor for consumer acceptance.

From a materials science perspective, the design strategy combined protein engineering with biomimetic inspiration. Researchers isolated and modified glutenin-like proteins, known for their natural tendency to form β-sheet-rich fibrils, to produce the amyloid-like structures. Advanced spectroscopy and electron microscopy analyses verified the alignment and morphology of the fibrils, revealing tightly packed, highly ordered structures that conferred tensile strength and barrier properties. Small-angle X-ray scattering further elucidated the hierarchical organization of the coatings at multiple length scales, confirming their homogeneity and stability under varying temperature and humidity conditions.

In addition to preservation, the coatings hold promise as a platform for functionalization. By incorporating natural antioxidants or enzymatic inhibitors into the protein matrix during assembly, the researchers demonstrated potential for active preservation—scavenging ethylene gas, a hormonal signal that accelerates fruit ripening, or neutralizing free radicals to prevent oxidative damage. This active approach transcends passive barrier methods, introducing dynamic control over postharvest physiology.

Economically, the scalability of this protein coating technology appears promising. Raw materials are abundant and derived from renewable agricultural proteins, reducing costs relative to synthetic polymers. The process employs aqueous, mild conditions compatible with industrial food processing workflows. Given its biocompatibility and biodegradability, the coating also addresses environmental concerns associated with plastic packaging waste.

Further research is underway to optimize application methods, including spray and dip-coating techniques, ensuring uniform coverage and minimal material usage. Long-term storage studies and transportation simulations aim to validate the coating’s performance in real-world supply chain scenarios. Regulatory approvals and consumer education efforts will be critical to commercial adoption.

This innovation arrives at a pivotal moment as the global community grapples with food security and sustainability challenges. Postharvest losses account for an estimated one-third of total food produced worldwide, exerting immense environmental and economic burdens. Technologies that can safely and naturally prolong the freshness of fruits have the potential to reduce wasted resources, lower greenhouse gas emissions associated with discarded food, and improve accessibility of nutritious foods.

In summarizing the potential impact, the amyloid-like protein coating technology bridges cutting-edge protein chemistry with practical agricultural applications. It offers a versatile, scalable, and environmentally sound tool to extend fruit freshness. By harnessing the ordered architecture and functional versatility of amyloid fibrils, this approach challenges conventional paradigms and opens new avenues for bioinspired preservation strategies.

As we witness the convergence of molecular design, sustainable materials science, and food technology, such innovations underscore the powerful role of interdisciplinary research in solving complex global issues. The amyloid-like protein coatings not only promise to keep fruits fresher for longer but also embody a broader shift toward bioengineered solutions that align with ecological and health imperatives.

Looking ahead, the integration of smart sensors and responsive biopolymers could enhance the versatility of such coatings, enabling fruits to communicate ripeness status or respond autonomously to environmental stresses. The foundational work laid by this study sets the stage for a new era where nature-derived materials and synthetic biology converge to transform food systems, extend shelf life, and reduce waste.

In conclusion, this pioneering research marks a significant milestone that could redefine fruit preservation. By elegantly leveraging the structural and functional attributes of amyloid-like proteins, scientists have crafted a coating that not only preserves fruit freshness but also fits seamlessly within the broader goals of sustainability and consumer safety. As this technology progresses toward commercialization, it holds the promise to create substantial benefits across agriculture, industry, and society at large.

Subject of Research: Preservation of fruit freshness using amyloid-like protein coatings.

Article Title: Preserving fruit freshness with amyloid-like protein coatings.

Article References:
Feng, N., Zhang, J., Tian, J. et al. Preserving fruit freshness with amyloid-like protein coatings. Nat Commun 16, 5060 (2025). https://doi.org/10.1038/s41467-025-60382-4

Image Credits: AI Generated

Tags: agricultural supply chain innovationsamyloid protein coatingsbiodegradable food coatingsenhancing freshness of perishable produceenvironmental sustainability in food storageextending shelf life of fruitsfruit preservation technologymicrobial growth prevention methodsnovel food preservation methodspostharvest handling solutionsreducing food wasteself-assembling protein structures

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