Yeast Surface Display Stabilizes Influenza Antigen for Oral Delivery
A study in AMB Express demonstrates that a conserved influenza mini-HA antigen can be stably displayed on Saccharomyces cerevisiae for ...
Tag: Vaccine development
Researchers Rescue Porcine-Bovine Rotavirus Reassortant
Researchers isolated a porcine-bovine reassortant rotavirus from a piglet in China and established a reverse genetics system to study its ...
Red Microalga Expresses Dengue Structural Antigens Across All Four Serotypes
Researchers have demonstrated the successful expression of recombinant dengue virus structural antigens from all four serotypes in the red microalga ...
Rotavirus evolution balances conservation and change across its eleven proteins
A genome-wide analysis of amino acid substitutions in human group A rotavirus shows that conservative changes dominate the viral proteome ...
African swine fever virus deploys layered immune evasion that stalls vaccine progress
A new review maps how African swine fever virus dismantles interferon signaling, inflammatory pathways, antigen presentation and lymphocyte function, explaining ...
From Lab Dishes to Ferrets: Mapping the Preclinical Models of SFTS Virus
A new review evaluates the cellular and animal models used to study Bandavirus dabieense infection and argues that no single ...
New Chicken-Origin Tembusu Virus Strain Shows Distinct Genes and Pathogenicity in China
Researchers in China isolated a chicken-origin cluster 3.2 Tembusu virus strain with a unique envelope protein substitution that caused neurological ...
Optimized Fermentation Boosts Streptococcus suis Biomass for Inactivated Vaccine Testing
An optimized 14-L fermentation process for Streptococcus suis serotype 31 achieved 1.51 × 10¹⁰ CFU/mL and produced an inactivated vaccine ...
$16.4 Million NIH Award Launches Multi-Institution Center for Hepatitis C Vaccine Design
The NIH has awarded $16.4 million over five years to a new multi-institution U19 center led by Scripps Research to ...
China’s arbovirus landscape in 2026: immunity, outbreaks and vaccine lessons
A 2026 review synthesizes immune mechanisms, vaccine progress and climate-driven risks for dengue, Zika, Japanese encephalitis and chikungunya in China.
Researchers watch a virus-like particle assemble itself, one molecule at a time
Oxford scientists have directly observed individual virus-like particles assembling step by step, revealing how simple molecular interactions reliably build complex ...
Genomic Surveillance and Structural Analysis Drive Next Generation of Viral Diagnostics and Vaccines
Molecular and phylogenetic insights are essential for advancing diagnostics and vaccine development by providing high-resolution data on viral evolution and ...
Lyme Disease Rates in Europe Far Exceed Surveillance Figures, Landmark Study Finds
A prospective active surveillance study across six European countries found medically attended Lyme borreliosis incidence of about 660 per 100,000 ...
Chimeric rodent malaria parasites put P. vivax vaccine antigens SSP3 and SPECT1 to the test
Transgenic Plasmodium berghei lines expressing P. vivax antigens SSP3 and SPECT1 developed normally and enabled preclinical testing that revealed modest ...
Parasite Protein’s Tail Holds the Key to Membrane Binding and Vaccine Design
A new PLOS Pathogens study shows that the short N-terminal region of alpha-1 giardin, a vaccine candidate protein from the ...
mRNA Vaccines Deliver Lasting Protection Against Tapeworm Disease
New EG95-based mRNA-lipid nanoparticle vaccines induced stronger and longer-lasting immunity against cystic echinococcosis than conventional subunit vaccines in mice and ...
Mass Spectrometry Uncovers Hidden Bacterial Targets of Tularemia Immunity
Using mass spectrometry-based immunopeptidomics, researchers identified 57 MHC-II peptides from 23 Francisella tularensis proteins and pinpointed ten immunogenic CD4 T ...
Adenovirus Types 3 and 7 Drive Winter Pneumonia Surge in Hospitalized Chinese Children
A three-year genomic surveillance study in Tianjin found that adenovirus types 3 and 7 dominate pediatric respiratory infections, with a ...
How Antigen Processing Shapes SARS-CoV-2 CD4+ T Cell Responses
In a groundbreaking study published in “Genome Medicine,” researchers have unveiled significant insights into the mechanisms by which CD4+ T ...
Machine Learning Transforms B-Cell Epitope Prediction
In the rapidly evolving landscape of immunology, B-cell epitope prediction has emerged as a crucial focus, particularly with advancements in ...
