Tag: tumor metabolism

A University of Oklahoma study supported by the National Cancer Institute is investigating how high-fat diets weaken anti-tumor immune responses ...

A computationally derived five-gene prognostic risk signature for osteosarcoma showed significant survival stratification in its discovery cohort but failed to ...

A review in Discover Oncology examines how IGF/IGF-1R signaling influences tumor metabolism and immune regulation, noting that effects are context-dependent ...

A retrospective study of 248 breast cancer patients found that HER2-low, HER2-zero, and HER2-overexpressing tumors show distinct glucose metabolism patterns ...

A cross-sectional study of 166 newly diagnosed breast cancer patients found that higher adiposity and low muscle mass correlated with ...

Intravesical alpha1-oleate treatment strongly suppressed glucose- and lipid-metabolism genes and altered adiponectin and leptin signaling in bladder tumor tissue compared ...

An optimized on-tissue derivatization workflow using 4-APEBA and EDC enables confident MALDI-MSI mapping of carbonyl- and carboxyl-containing metabolites in mouse ...

A new review maps how protein arginine methyltransferases both cooperate and antagonize one another in tumors, arguing that multi-target and ...

Salidroside suppresses gastric cancer cell proliferation and tumor growth by upregulating miR-1343-3p, which directly targets the mitochondrial citrate transporter SLC25A1 ...

CRISPR-engineered cervical cancer cells carrying the PIK3CA-E545K mutation show coordinated immune signaling and metabolic rewiring, driven by suppressed lipid biosynthesis ...

In vivo isotope tracing in KRAS-driven lung cancer mouse models shows that tumor fat synthesis draws mainly on lactate and ...

A new study finds that the transcription factor FOXA1 suppresses ferroptosis in cervical cancer cells by directly activating SLC7A11 transcription, ...

A new Cellular Oncology study reports that the tumor suppressor TNFAIP3 restrains lactylation-linked DNA damage repair and increases ovarian cancer ...

A new review in Medical Oncology details how the mitochondrial transporter SLC25A39 links glutathione import, iron-sulfur cluster assembly and tumor ...

Integrated transcriptomic and cell-line analyses link GSTK1 expression to favorable gastric cancer prognosis and to IL-6/JAK2/STAT3 signaling, glycolysis-related proteins, and ...

A machine-learning and proteomics study associates high peptide deformylase expression with immune-cold colorectal cancer, low immune infiltration, elevated oxidative phosphorylation ...

A review frames microbiome-derived metabolites and mitochondrial activity as a proposed research axis for glioblastoma metabolism and immunity, while noting ...

Cell, tissue and mouse experiments link elevated SWAP70 to advanced human liver tumors and show that it supports hepatocellular carcinoma ...

A new review details how the NRF2 transcription factor shields cancer cells from iron-dependent ferroptotic death and how natural and ...

A UCLA study found that the dietary supplement calcium alpha-ketoglutarate slowed lung tumor growth in female mice while enlarging tumors ...