CSF Vesicle Metabolomics Tracks Evolving Biochemical Changes After Severe Brain Injury
Untargeted metabolomics of cerebrospinal fluid small extracellular vesicles from severe TBI patients reveals distinct temporal metabolic changes at Days 1, ...
Tag: Traumatic Brain Injury
After Brain Injury, Astrocytes Ship Mitochondria to Struggling Neurons
A mouse study of traumatic brain injury found that astrocytes increase mitochondrial transfer to neurons via extracellular vesicles, a response ...
Ultrasound Eye Measurement Tracks Brain Injury Severity, But ICP Validity Remains Unproven
A new letter argues that optic nerve sheath ultrasound correlates with brain injury severity but has not been validated against ...
Sliding Brain-Skull Interface Boosts Biofidelity of Finite Element Head Model
Researchers rebuilt the brain-skull interface of an atlas-based finite element head model with a smooth skull and sliding contact, then ...
New Guidelines Tackle Penetrating Brain Injury, Urging Doctors to Reject Nihilism
A new neurocritical care viewpoint distills the updated Brain Trauma Foundation guidelines for penetrating brain injury, where most evidence remains ...
Randomized trial compares autologous and synthetic grafts for cranial duraplasty safety
A prospective randomized study of 100 patients in Central India found no statistically significant difference in 30-day complications between autologous ...
Astragaloside IV Improves Cognition After Brain Injury in Mice, Study Finds
A new mouse study finds that the herbal compound astragaloside IV improved learning, memory, and synaptic structure after traumatic brain ...
Scoping review maps how agitation after traumatic brain injury is managed
A scoping review of 13 studies finds no standardised approach to agitation after traumatic brain injury, with olanzapine and valproic ...
MRI Signal Reveals Meningeal Injury After Traumatic Brain Injury
A retrospective MRI study of 186 predominantly mild traumatic brain injury patients found elevated extra-axial ADC in 39% at baseline, ...
Intracranial EEG Spots Hidden Seizures in Acute Brain Injury, Meta-analysis Finds
A meta-analysis of 864 patients found intracranial EEG detected seizures and epileptic patterns far more often than surface EEG in ...
Machine learning model predicts in-hospital complications after traumatic brain injury
A retrospective study of 186 traumatic brain injury patients found that a model using four admission variables predicted in-hospital complications ...
Journal Retracts 2018 Valproic Acid Brain Injury Study Over Image Integrity Concerns
Frontiers in Molecular Neuroscience has retracted a 2018 study on valproic acid and traumatic brain injury after an investigation found ...
QEEG-Guided Low-Intensity Magnetic Stimulation Shows Preliminary Brain and Cognitive Changes in One Athlete With Chronic Traumatic Brain Injury
A single-case study reports that individualized, QEEG-guided low-intensity transcranial magnetic stimulation was associated with altered brain wave patterns and improved ...
MRI Brain Age After Traumatic Brain Injury: Systematic Review Finds Mixed, Hard-to-Compare Evidence
A new systematic review finds that MRI-derived brain age differences after adult traumatic brain injury are inconsistent across studies and ...
Traumatic Venous Sinus Thrombosis: Anticoagulation Benefit Remains Uncertain in 14-Year Study
A retrospective study of 138 head trauma patients in Melbourne found traumatic cerebral venous sinus thrombosis in 0.9% of TBI ...
New Four-Pillar Framework Shows Strong Performance in Characterizing Traumatic Brain Injury
A four-pillar framework for characterizing traumatic brain injury showed strong diagnostic and prognostic performance in two large prospective cohort studies, ...
Online Flipped Classroom Matches Simulation for Teaching Neurotrauma Nursing Skills
A quasi-experimental study found nursing students taught through an online flipped classroom with case-based learning achieved slightly higher post-test knowledge ...
Intracranial pressure alone cannot capture the complexity of traumatic brain injury, researchers argue
A new perspective in Critical Care argues that a single intracranial pressure threshold is an insufficient foundation for managing severe ...
Functional Recovery Alone Misses Social and Emotional Struggles After Serious Brain Injury
A study of 138 adults with moderate-to-severe traumatic brain injury finds that the GOSE functional scale strongly tracks independence, thinking, ...
New MRI-to-Model Pipeline Builds Personalized Brain Simulations from Rugby Player Scans
A New Zealand research team has developed a reproducible pipeline that converts MRI scans of adolescent rugby players into a ...
